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| Home > Publications Database > The gut microbiome in Parkinson's disease | Das Darmmikrobiom bei der Parkinson-Krankheit > print |
| Home > Publications Database > The gut microbiome in Parkinson's disease | Das Darmmikrobiom bei der Parkinson-Krankheit > print |
| 001 | 140488 | ||
| 005 | 20240722132448.0 | ||
| 024 | 7 | _ | |a 10.1007/s00115-018-0601-6 |2 doi |
| 024 | 7 | _ | |a pmid:30171304 |2 pmid |
| 024 | 7 | _ | |a 0028-2804 |2 ISSN |
| 024 | 7 | _ | |a 1433-0407 |2 ISSN |
| 024 | 7 | _ | |a altmetric:47560826 |2 altmetric |
| 037 | _ | _ | |a DZNE-2020-06810 |
| 041 | _ | _ | |a ger |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Bedarf, Janis |0 P:(DE-2719)2811747 |b 0 |e First author |u dzne |
| 245 | _ | _ | |a The gut microbiome in Parkinson's disease | Das Darmmikrobiom bei der Parkinson-Krankheit |
| 260 | _ | _ | |a Heidelberg |c 2019 |b Springer |
| 264 | _ | 1 | |3 online |2 Crossref |b Springer Science and Business Media LLC |c 2018-08-31 |
| 264 | _ | 1 | |3 print |2 Crossref |b Springer Science and Business Media LLC |c 2019-02-01 |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1721647432_12030 |2 PUB:(DE-HGF) |x Review Article |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a The vast majority of Parkinson's disease (PD) cases are of sporadic origin and despite extensive research in recent years, the etiology still remains unclear. Several current case control studies are aiming to characterize a putative PD-specific composition of the gut microbiome, reflecting the potential relevance of microbiota in the pathogenesis of PD. Although methodologies and cohort sizes differed, the currently available studies showed reproducible or consistent results in terms of PD-specific alterations to the intestinal bacteria. By applying metagenomic sequencing procedures, it is even possible to distinguish PD cases from healthy individuals at a very early disease stage by means of individually modified microbiota. Among others, microbiota that are associated with an altered intestinal barrier or immune function, such as Akkermansia, Lactobacillus, Faecalibacterium and Prevotella were significantly over-represented or under-represented. There may even be a prodromal microbiome, as a comparable microbial shift is also found in patients with rapid eye movement (REM) sleep behavior disorder (RBD), a risk factor for the later development of synucleinopathies, such as PD. |
| 536 | _ | _ | |a 342 - Disease Mechanisms and Model Systems (POF3-342) |0 G:(DE-HGF)POF3-342 |c POF3-342 |f POF III |x 0 |
| 536 | _ | _ | |a 344 - Clinical and Health Care Research (POF3-344) |0 G:(DE-HGF)POF3-344 |c POF3-344 |f POF III |x 1 |
| 542 | _ | _ | |i 2018-08-31 |2 Crossref |u http://www.springer.com/tdm |
| 588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
| 650 | _ | 2 | |a Case-Control Studies |2 MeSH |
| 650 | _ | 2 | |a Gastrointestinal Microbiome |2 MeSH |
| 650 | _ | 2 | |a Humans |2 MeSH |
| 650 | _ | 2 | |a Metagenome |2 MeSH |
| 650 | _ | 2 | |a Parkinson Disease: diagnosis |2 MeSH |
| 650 | _ | 2 | |a Parkinson Disease: microbiology |2 MeSH |
| 650 | _ | 2 | |a REM Sleep Behavior Disorder: microbiology |2 MeSH |
| 700 | 1 | _ | |a Hildebrand, F. |b 1 |
| 700 | 1 | _ | |a Goeser, F. |b 2 |
| 700 | 1 | _ | |a Bork, P. |b 3 |
| 700 | 1 | _ | |a Wüllner, U. |0 P:(DE-2719)2000056 |b 4 |e Last author |u dzne |
| 773 | 1 | 8 | |a 10.1007/s00115-018-0601-6 |b : Springer Science and Business Media LLC, 2018-08-31 |n 2 |p 160-166 |3 journal-article |2 Crossref |t Der Nervenarzt |v 90 |y 2018 |x 0028-2804 |
| 773 | _ | _ | |a 10.1007/s00115-018-0601-6 |g Vol. 90, no. 2, p. 160 - 166 |0 PERI:(DE-600)1462945-8 |n 2 |q 90:2<160 - 166 |p 160-166 |t Der Nervenarzt |v 90 |y 2019 |x 0028-2804 |
| 856 | 4 | _ | |u https://pub.dzne.de/record/140488/files/DZNE-2020-06810.pdf |
| 856 | 4 | _ | |u https://pub.dzne.de/record/140488/files/DZNE-2020-06810.pdf?subformat=pdfa |x pdfa |
| 909 | C | O | |p VDB |o oai:pub.dzne.de:140488 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 0 |6 P:(DE-2719)2811747 |
| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 4 |6 P:(DE-2719)2000056 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-342 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Disease Mechanisms and Model Systems |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Erkrankungen des Nervensystems |1 G:(DE-HGF)POF3-340 |0 G:(DE-HGF)POF3-344 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-300 |4 G:(DE-HGF)POF |v Clinical and Health Care Research |x 1 |
| 914 | 1 | _ | |y 2019 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2022-11-12 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2022-11-12 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Clarivate Analytics Master Journal List |d 2022-11-12 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |d 2022-11-12 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |d 2022-11-12 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1110 |2 StatID |b Current Contents - Clinical Medicine |d 2022-11-12 |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b NERVENARZT : 2021 |d 2022-11-12 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0600 |2 StatID |b Ebsco Academic Search |d 2022-11-12 |
| 915 | _ | _ | |a Peer Review |0 StatID:(DE-HGF)0030 |2 StatID |b ASC |d 2022-11-12 |
| 915 | _ | _ | |a IF < 5 |0 StatID:(DE-HGF)9900 |2 StatID |d 2022-11-12 |
| 920 | 1 | _ | |0 I:(DE-2719)1013022 |k AG Tamgüney 2 |l Prion and prion-like diseases |x 0 |
| 920 | 1 | _ | |0 I:(DE-2719)1011302 |k AG Wüllner |l Biomarker Parkinson's Disease |x 1 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-2719)1013022 |
| 980 | _ | _ | |a I:(DE-2719)1011302 |
| 980 | _ | _ | |a UNRESTRICTED |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.26702 |2 Crossref |o 10.1002/mds.26702 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1186/s13073-017-0428-y |2 Crossref |o 10.1186/s13073-017-0428-y |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.molmed.2014.05.002 |2 Crossref |o 10.1016/j.molmed.2014.05.002 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1101/cshperspect.a023630 |2 Crossref |o 10.1101/cshperspect.a023630 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrmicro2876 |2 Crossref |o 10.1038/nrmicro2876 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/s41564-017-0072-8 |2 Crossref |o 10.1038/s41564-017-0072-8 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.nbd.2012.09.007 |2 Crossref |o 10.1016/j.nbd.2012.09.007 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1111/2049-632X.12170 |2 Crossref |o 10.1111/2049-632X.12170 |
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| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.26942 |2 Crossref |o 10.1002/mds.26942 |
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| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1371/journal.pone.0076520 |2 Crossref |o 10.1371/journal.pone.0076520 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.chom.2015.03.005 |2 Crossref |o 10.1016/j.chom.2015.03.005 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.26307 |2 Crossref |o 10.1002/mds.26307 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nrneurol.2015.197 |2 Crossref |o 10.1038/nrneurol.2015.197 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/nm.4102 |2 Crossref |o 10.1038/nm.4102 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1007/s11427-016-9001-4 |2 Crossref |o 10.1007/s11427-016-9001-4 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1038/srep13888 |2 Crossref |o 10.1038/srep13888 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.febslet.2015.10.023 |2 Crossref |o 10.1016/j.febslet.2015.10.023 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1097/MCO.0b013e32833eebe5 |2 Crossref |o 10.1097/MCO.0b013e32833eebe5 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3389/fcell.2015.00085 |2 Crossref |o 10.3389/fcell.2015.00085 |
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| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1002/mds.26069 |2 Crossref |o 10.1002/mds.26069 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.immuni.2013.12.007 |2 Crossref |o 10.1016/j.immuni.2013.12.007 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1523/JNEUROSCI.1787-16.2017 |2 Crossref |o 10.1523/JNEUROSCI.1787-16.2017 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1016/j.parkreldis.2016.08.019 |2 Crossref |o 10.1016/j.parkreldis.2016.08.019 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1136/gutjnl-2015-309618 |2 Crossref |o 10.1136/gutjnl-2015-309618 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.3945/ajcn.116.146928 |2 Crossref |o 10.3945/ajcn.116.146928 |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1111/j.1574-6941.2011.01252.x |2 Crossref |o 10.1111/j.1574-6941.2011.01252.x |
| 999 | C | 5 | |9 -- missing cx lookup -- |a 10.1111/jnc.13646 |2 Crossref |o 10.1111/jnc.13646 |
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