%0 Journal Article
%A Vöglein, Jonathan
%A Noachtar, Soheyl
%A McDade, Eric
%A Quaid, Kimberly A
%A Salloway, Stephen
%A Ghetti, Bernardino
%A Noble, James
%A Berman, Sarah
%A Chhatwal, Jasmeer
%A Mori, Hiroshi
%A Fox, Nick
%A Allegri, Ricardo
%A Masters, Colin L
%A Buckles, Virginia
%A Ringman, John M
%A Rossor, Martin
%A Schofield, Peter R
%A Sperling, Reisa
%A Jucker, Mathias
%A Laske, Christoph
%A Paumier, Katrina
%A Morris, John C
%A Bateman, Randall J
%A Levin, Johannes
%A Danek, Adrian
%A Network, Dominantly Inherited Alzheimer
%T Seizures as an early symptom of autosomal dominant Alzheimer's disease.
%J Neurobiology of aging
%V 76
%@ 0197-4580
%C Amsterdam [u.a.]
%I Elsevier Science
%M DZNE-2020-06833
%P 18-23
%D 2019
%X Our objective was to assess the reported history of seizures in cognitively asymptomatic mutation carriers for autosomal dominant Alzheimer's disease (ADAD) and the predictive value of seizures for mutation carrier status in cognitively asymptomatic first-degree relatives of ADAD patients. Seizure occurrence in the Dominantly Inherited Alzheimer Network observational study was correlated with mutation carrier status in cognitively asymptomatic subjects. Of 276 cognitively asymptomatic individuals, 11 (4
%K Adult
%K Alzheimer Disease: complications
%K Alzheimer Disease: genetics
%K Female
%K Genes, Dominant: genetics
%K Genetic Association Studies
%K Heterozygote
%K Humans
%K Male
%K Mutation: genetics
%K Observational Studies as Topic
%K Predictive Value of Tests
%K Risk
%K Seizures: etiology
%K Seizures: genetics
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:30616208
%2 pmc:PMC6572755
%R 10.1016/j.neurobiolaging.2018.11.022
%U https://pub.dzne.de/record/140511