TY  - JOUR
AU  - Vöglein, Jonathan
AU  - Noachtar, Soheyl
AU  - McDade, Eric
AU  - Quaid, Kimberly A
AU  - Salloway, Stephen
AU  - Ghetti, Bernardino
AU  - Noble, James
AU  - Berman, Sarah
AU  - Chhatwal, Jasmeer
AU  - Mori, Hiroshi
AU  - Fox, Nick
AU  - Allegri, Ricardo
AU  - Masters, Colin L
AU  - Buckles, Virginia
AU  - Ringman, John M
AU  - Rossor, Martin
AU  - Schofield, Peter R
AU  - Sperling, Reisa
AU  - Jucker, Mathias
AU  - Laske, Christoph
AU  - Paumier, Katrina
AU  - Morris, John C
AU  - Bateman, Randall J
AU  - Levin, Johannes
AU  - Danek, Adrian
AU  - Network, Dominantly Inherited Alzheimer
TI  - Seizures as an early symptom of autosomal dominant Alzheimer's disease.
JO  - Neurobiology of aging
VL  - 76
SN  - 0197-4580
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - DZNE-2020-06833
SP  - 18-23
PY  - 2019
AB  - Our objective was to assess the reported history of seizures in cognitively asymptomatic mutation carriers for autosomal dominant Alzheimer's disease (ADAD) and the predictive value of seizures for mutation carrier status in cognitively asymptomatic first-degree relatives of ADAD patients. Seizure occurrence in the Dominantly Inherited Alzheimer Network observational study was correlated with mutation carrier status in cognitively asymptomatic subjects. Of 276 cognitively asymptomatic individuals, 11 (4
KW  - Adult
KW  - Alzheimer Disease: complications
KW  - Alzheimer Disease: genetics
KW  - Female
KW  - Genes, Dominant: genetics
KW  - Genetic Association Studies
KW  - Heterozygote
KW  - Humans
KW  - Male
KW  - Mutation: genetics
KW  - Observational Studies as Topic
KW  - Predictive Value of Tests
KW  - Risk
KW  - Seizures: etiology
KW  - Seizures: genetics
LB  - PUB:(DE-HGF)16
C6  - pmid:30616208
C2  - pmc:PMC6572755
DO  - DOI:10.1016/j.neurobiolaging.2018.11.022
UR  - https://pub.dzne.de/record/140511
ER  -