% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Merhav:140513,
      author       = {Merhav, Maayan and Riemer, Martin and Wolbers, Thomas},
      title        = {{S}patial updating deficits in human aging are associated
                      with traces of former memory representations.},
      journal      = {Neurobiology of aging},
      volume       = {76},
      issn         = {0197-4580},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DZNE-2020-06835},
      pages        = {53-61},
      year         = {2019},
      abstract     = {The ability to update spatial memories is important for
                      everyday situations, such as remembering where we left our
                      keys or parked our car. Although rodent studies have
                      suggested that old age might impair spatial updating, direct
                      evidence for such a deficit in humans is missing. Here, we
                      tested whether spatial updating deficits occur in human
                      aging, whether the learning mode influences spatial
                      updating, and what mnemonic mechanism underlies the presumed
                      deficits. To address these questions, younger and older
                      participants had to indicate the latest location of
                      relocated items, following either incidental or intentional
                      learning. Using eye tracking, we further quantified memory
                      traces of the original and updated locations. We found that
                      older participants were selectively impaired in recalling
                      locations of relocated items. Furthermore, they depicted
                      relatively stronger representations of the original
                      locations, which were correlated with their spatial updating
                      deficits. The findings demonstrate that stronger
                      representations of former spatial contexts can impair
                      spatial updating in aging, a mechanism that can help explain
                      the commonly observed age-related decline in spatial
                      memory.},
      keywords     = {Adult / Aged / Aging: psychology / Female / Humans /
                      Learning: physiology / Male / Memory Disorders: psychology /
                      Mental Recall / Proactive Inhibition / Space Perception:
                      physiology / Spatial Memory: physiology / Spatial
                      Navigation: physiology / Young Adult},
      cin          = {AG Wolbers},
      ddc          = {610},
      cid          = {I:(DE-2719)1310002},
      pnm          = {344 - Clinical and Health Care Research (POF3-344)},
      pid          = {G:(DE-HGF)POF3-344},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30703626},
      doi          = {10.1016/j.neurobiolaging.2018.12.010},
      url          = {https://pub.dzne.de/record/140513},
}