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@ARTICLE{Mattern:140591,
      author       = {Mattern, Hendrik and Sciarra, Alessandro and Lüsebrink,
                      Falk and Acosta-Cabronero, Julio and Speck, Oliver},
      title        = {{P}rospective motion correction improves high-resolution
                      quantitative susceptibility mapping at 7{T}.},
      journal      = {Magnetic resonance in medicine},
      volume       = {81},
      number       = {3},
      issn         = {0740-3194},
      address      = {New York, NY [u.a.]},
      publisher    = {Wiley-Liss},
      reportid     = {DZNE-2020-06913},
      pages        = {1605-1619},
      year         = {2019},
      abstract     = {Recent literature has shown the potential of
                      high-resolution quantitative susceptibility mapping (QSM)
                      with ultra-high field MRI for imaging the anatomy, the
                      vasculature, and investigating their magnetostatic
                      properties. Higher spatial resolutions, however, translate
                      to longer scans resulting, therefore, in higher
                      vulnerability to, and likelihood of, subject movement. We
                      propose a gradient-recalled echo sequence with prospective
                      motion correction (PMC) to address such limitation.Data from
                      4 subjects were acquired at 7T. The effect of small and
                      large motion on QSM with and without PMC was assessed
                      qualitatively and quantitatively. Full brain QSM and
                      QSM-based venograms with up to 0.33 mm isotropic voxel size
                      were reconstructed.With PMC, motion artifacts in QSM and
                      QSM-based venograms were largely eliminated, enabling-in
                      both large- and small-amplitude motion regimes-accurate
                      depiction of the cortex, vasculature, and other small
                      anatomical structures that are often blurred as a result of
                      head movement or indiscernible at lower image resolutions.
                      Quantitative analyses demonstrated that uncorrected motion
                      could bias regional susceptibility distributions, a trend
                      that was greatly reduced with PMC.Qualitatively, PMC
                      prevented image degradation because of motion artifacts,
                      providing highly detailed QSM images and venograms.
                      Quantitatively, PMC increased the reproducibility of
                      susceptibility measures.},
      keywords     = {Adult / Algorithms / Artifacts / Brain: diagnostic imaging
                      / Brain Mapping: methods / Female / Head Movements / Humans
                      / Image Interpretation, Computer-Assisted: methods / Image
                      Processing, Computer-Assisted: methods / Magnetic Resonance
                      Imaging / Magnetics / Male / Motion / Reproducibility of
                      Results / Vision, Ocular},
      cin          = {AG Nestor / AG Düzel},
      ddc          = {610},
      cid          = {I:(DE-2719)1310001 / I:(DE-2719)5000006},
      pnm          = {344 - Clinical and Health Care Research (POF3-344)},
      pid          = {G:(DE-HGF)POF3-344},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30298692},
      doi          = {10.1002/mrm.27509},
      url          = {https://pub.dzne.de/record/140591},
}