% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Brgers:140636,
      author       = {Bürgers, Jana and Pavlova, Irina and Rodriguez-Gatica,
                      Juan E and Henneberger, Christian and Oeller, Marc and
                      Ruland, Jan A and Siebrasse, Jan P and Kubitscheck, Ulrich
                      and Schwarz, Martin K},
      title        = {{L}ight-sheet fluorescence expansion microscopy: fast
                      mapping of neural circuits at super resolution.},
      journal      = {Neurophotonics},
      volume       = {6},
      number       = {01},
      issn         = {2329-423X},
      address      = {Bellingham, Wash.},
      publisher    = {SPIE},
      reportid     = {DZNE-2020-06958},
      pages        = {1},
      year         = {2019},
      abstract     = {The goal of understanding the architecture of neural
                      circuits at the synapse level with a brain-wide perspective
                      has powered the interest in high-speed and large
                      field-of-view volumetric imaging at subcellular resolution.
                      Here, we developed a method combining tissue expansion and
                      light-sheet fluorescence microscopy to allow extended
                      volumetric super resolution high-speed imaging of large
                      mouse brain samples. We demonstrate the capabilities of this
                      method by performing two color fast volumetric super
                      resolution imaging of mouse CA1 and dentate gyrus
                      molecular-, granule cell-, and polymorphic layers. Our
                      method enables an exact evaluation of granule cell and
                      neurite morphology within the context of large cell
                      ensembles spanning several orders of magnitude in
                      resolution. We found that imaging a brain region of 1   
                      mm 3 in super resolution using light-sheet fluorescence
                      expansion microscopy is about 17-fold faster than imaging
                      the same region by a current state-of-the-art
                      high-resolution confocal laser scanning microscope.},
      cin          = {U Preclinical Researchers - Bonn},
      cid          = {I:(DE-2719)7000005},
      pnm          = {342 - Disease Mechanisms and Model Systems (POF3-342)},
      pid          = {G:(DE-HGF)POF3-342},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:30796881},
      pmc          = {pmc:PMC6368534},
      doi          = {10.1117/1.NPh.6.1.015005},
      url          = {https://pub.dzne.de/record/140636},
}