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@ARTICLE{Graf:140642,
author = {Graf, Heiko and Malejko, Kathrin and Metzger, Coraline
Danielle and Walter, Martin and Grön, Georg and Abler,
Birgit},
title = {{S}erotonergic, {D}opaminergic, and {N}oradrenergic
{M}odulation of {E}rotic {S}timulus {P}rocessing in the
{M}ale {H}uman {B}rain.},
journal = {Journal of Clinical Medicine},
volume = {8},
number = {3},
issn = {2077-0383},
address = {Basel},
publisher = {MDPI},
reportid = {DZNE-2020-06964},
pages = {363},
year = {2019},
abstract = {Human sexual behavior is mediated by a complex interplay of
cerebral and spinal centers, as well as hormonal,
peripheral, and autonomic functions. Neuroimaging studies
identified central neural signatures of human sexual
responses comprising neural emotional, motivational,
autonomic, and cognitive components. However, empirical
evidence regarding the neuromodulation of these neural
signatures of human sexual responses was scarce for decades.
Pharmacological functional magnetic resonance imaging (fMRI)
provides a valuable tool to examine the interaction between
neuromodulator systems and functional network anatomy
relevant for human sexual behavior. In addition, this
approach enables the examination of potential neural
mechanisms regarding treatment-related sexual dysfunction
under psychopharmacological agents. In this article, we
introduce common neurobiological concepts regarding cerebral
sexual responses based on neuroimaging findings and we
discuss challenges and findings regarding investigating the
neuromodulation of neural sexual stimulus processing. In
particular, we summarize findings from our research program
investigating how neural correlates of sexual stimulus
processing are modulated by serotonergic, dopaminergic, and
noradrenergic antidepressant medication in healthy males.},
subtyp = {Review Article},
cin = {AG Düzel},
ddc = {610},
cid = {I:(DE-2719)5000006},
pnm = {344 - Clinical and Health Care Research (POF3-344)},
pid = {G:(DE-HGF)POF3-344},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:30875818},
pmc = {pmc:PMC6463265},
doi = {10.3390/jcm8030363},
url = {https://pub.dzne.de/record/140642},
}