TY  - JOUR
AU  - Sohrabi, Hamid R
AU  - Weinborn, Michael
AU  - Laske, Christoph
AU  - Bates, Kristyn A
AU  - Christensen, Daniel
AU  - Taddei, Kevin
AU  - Rainey-Smith, Stephanie R
AU  - Brown, Belinda M
AU  - Gardener, Samantha L
AU  - Laws, Simon M
AU  - Martins, Georgia
AU  - Burnham, Samantha C
AU  - Bucks, Romola S
AU  - Reisberg, Barry
AU  - Lautenschlager, Nicola T
AU  - Foster, Jonathan
AU  - Martins, Ralph N
TI  - Subjective memory complaints predict baseline but not future cognitive function over three years: results from the Western Australia Memory Study.
JO  - International psychogeriatrics
VL  - 31
IS  - 04
SN  - 1041-6102
CY  - Cambridge
PB  - Cambridge Univ. Press
M1  - DZNE-2020-06980
SP  - 513-525
PY  - 2019
AB  - ABSTRACTBackground:This study investigated the characteristics of subjective memory complaints (SMCs) and their association with current and future cognitive functions.A cohort of 209 community-dwelling individuals without dementia aged 47-90 years old was recruited for this 3-year study. Participants underwent neuropsychological and clinical assessments annually. Participants were divided into SMCs and non-memory complainers (NMCs) using a single question at baseline and a memory complaints questionnaire following baseline, to evaluate differential patterns of complaints. In addition, comprehensive assessment of memory complaints was undertaken to evaluate whether severity and consistency of complaints differentially predicted cognitive function.SMC and NMC individuals were significantly different on various features of SMCs. Greater overall severity (but not consistency) of complaints was significantly associated with current and future cognitive functioning.SMC individuals present distinctive features of memory complaints as compared to NMCs. Further, the severity of complaints was a significant predictor of future cognition. However, SMC did not significantly predict change over time in this sample. These findings warrant further research into the specific features of SMCs that may portend subsequent neuropathological and cognitive changes when screening individuals at increased future risk of dementia.
LB  - PUB:(DE-HGF)16
C6  - pmid:30277188
DO  - DOI:10.1017/S1041610218001072
UR  - https://pub.dzne.de/record/140658
ER  -