000141060 001__ 141060
000141060 005__ 20240321220922.0
000141060 0247_ $$2doi$$a10.1016/j.dib.2017.10.024
000141060 0247_ $$2pmid$$apmid:29124088
000141060 0247_ $$2pmc$$apmc:PMC5671473
000141060 0247_ $$2altmetric$$aaltmetric:27768745
000141060 037__ $$aDZNE-2020-07382
000141060 041__ $$aEnglish
000141060 082__ $$a570
000141060 1001_ $$0P:(DE-HGF)0$$aBaker, Suzanne L$$b0$$eCorresponding author
000141060 245__ $$aConsiderations and code for partial volume correcting [18F]-AV-1451 tau PET data.
000141060 260__ $$aAmsterdam [u.a.]$$bElsevier$$c2017
000141060 264_1 $$2Crossref$$3print$$bElsevier BV$$c2017-12-01
000141060 3367_ $$2DRIVER$$aarticle
000141060 3367_ $$2DataCite$$aOutput Types/Journal article
000141060 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1709826311_6139
000141060 3367_ $$2BibTeX$$aARTICLE
000141060 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000141060 3367_ $$00$$2EndNote$$aJournal Article
000141060 520__ $$a[18F]-AV-1451 is a leading tracer used with positron emission tomography (PET) to quantify tau pathology. However, [18F]-AV-1451 shows 'off target' or non-specific binding, which we define as binding of the tracer in unexpected areas unlikely to harbor aggregated tau based on autopsy literature [1]. Along with caudate, putamen, pallidum and thalamus non-specific binding [2], [3], we have found binding in the superior portion of the cerebellar gray matter, leading us to use inferior cerebellar gray as the reference region. We also addressed binding in the posterior portion of the choroid plexus. PET signal unlikely to be associated with tau also occurs in skull, meninges and soft tissue (see e.g. [4]). We refer to [18F]-AV-1451 binding in the skull and meninges as extra-cortical hotspots (ECH) and find them near lateral and medial orbitofrontal, lateral occipital, inferior and middle temporal, superior and inferior parietal, and inferior cerebellar gray matter. Lastly, the choroid plexus also shows non-specific binding that bleeds into hippocampus. We are providing the code (http://www.runmycode.org/companion/view/2798) used to create different regions of interest (ROIs) that we then used to perform Partial Volume Correction (PVC) using the Rousset geometric transfer matrix method (GTM, [5]). This method was used in the companion article, 'Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's Disease' ([6], DOI 10.1016/j.neuroimage.2017.05.058).
000141060 536__ $$0G:(DE-HGF)POF3-344$$a344 - Clinical and Health Care Research (POF3-344)$$cPOF3-344$$fPOF III$$x0
000141060 542__ $$2Crossref$$i2017-12-01$$uhttps://www.elsevier.com/tdm/userlicense/1.0/
000141060 542__ $$2Crossref$$i2017-10-13$$uhttp://creativecommons.org/licenses/by/4.0/
000141060 588__ $$aDataset connected to CrossRef, PubMed,
000141060 7001_ $$0P:(DE-2719)2811815$$aMaaß, Anne$$b1$$udzne
000141060 7001_ $$0P:(DE-HGF)0$$aJagust, William J$$b2
000141060 77318 $$2Crossref$$3journal-article$$a10.1016/j.dib.2017.10.024$$b : Elsevier BV, 2017-12-01$$p648-657$$tData in Brief$$v15$$x2352-3409$$y2017
000141060 773__ $$0PERI:(DE-600)2786545-9$$a10.1016/j.dib.2017.10.024$$gVol. 15, p. 648 - 657$$p648-657$$q15<648 - 657$$tData in Brief$$v15$$x2352-3409$$y2017
000141060 7870_ $$0DZNE-2020-05825$$aMaaß, Anne et.al.$$dOrlando, Fla. : Academic Press, 2017$$iRelatedTo$$r$$tComparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease.
000141060 8564_ $$uhttps://pub.dzne.de/record/141060/files/DZNE-2020-07382.pdf$$yOpenAccess
000141060 8564_ $$uhttps://pub.dzne.de/record/141060/files/DZNE-2020-07382.pdf?subformat=pdfa$$xpdfa$$yOpenAccess
000141060 8567_ $$2Pubmed Central$$uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671473
000141060 909CO $$ooai:pub.dzne.de:141060$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
000141060 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2811815$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE
000141060 9131_ $$0G:(DE-HGF)POF3-344$$1G:(DE-HGF)POF3-340$$2G:(DE-HGF)POF3-300$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lErkrankungen des Nervensystems$$vClinical and Health Care Research$$x0
000141060 9141_ $$y2017
000141060 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2022-11-30
000141060 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2022-11-30
000141060 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000141060 915__ $$0StatID:(DE-HGF)0112$$2StatID$$aWoS$$bEmerging Sources Citation Index$$d2022-11-30
000141060 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2021-05-31T09:03:54Z
000141060 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2021-05-31T09:03:54Z
000141060 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2022-11-30
000141060 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000141060 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Blind peer review$$d2021-05-31T09:03:54Z
000141060 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2022-11-30
000141060 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2022-11-30
000141060 9201_ $$0I:(DE-2719)5000006$$kAG Düzel$$lClinical Neurophysiology and Memory$$x0
000141060 980__ $$ajournal
000141060 980__ $$aVDB
000141060 980__ $$aUNRESTRICTED
000141060 980__ $$aI:(DE-2719)5000006
000141060 9801_ $$aFullTexts