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@ARTICLE{Wegmann:141184,
author = {Wegmann, Susanne and Muller, Daniel J and Mandelkow,
Eckhard},
title = {{I}nvestigating fibrillar aggregates of {T}au protein by
atomic force microscopy.},
journal = {Methods in molecular biology},
volume = {849},
issn = {1064-3745},
address = {[Heidelberg]},
publisher = {[Springer]},
reportid = {DZNE-2020-07506},
isbn = {978-1-61779-550-3 (print)},
series = {Methods in Molecular Biology},
pages = {169-183},
year = {2012},
comment = {Amyloid Proteins / Sigurdsson, Einar M. (Editor) ; Totowa,
NJ : Humana Press, 2012, Chapter 12 ; ISSN:
1064-3745=1940-6029 ; ISBN:
978-1-61779-550-3=978-1-61779-551-0 ;
doi:10.1007/978-1-61779-551-0},
booktitle = {Amyloid Proteins / Sigurdsson, Einar
M. (Editor) ; Totowa, NJ : Humana
Press, 2012, Chapter 12 ; ISSN:
1064-3745=1940-6029 ; ISBN:
978-1-61779-550-3=978-1-61779-551-0 ;
doi:10.1007/978-1-61779-551-0},
abstract = {Atomic force microscopy (AFM) has been used in numerous
studies to visualize and analyze the structure and
conformation of biological samples, from single molecules to
biopolymers to cells. The possibility to analyze native
samples without fixation, staining and in physiological
buffer conditions, combined with the sub-nanometer
resolution, makes AFM a versatile tool for the analysis of
protein aggregation and amyloid structures. Here, we
describe the application of AFM to study fibrillar Tau
protein aggregates.},
keywords = {Adsorption / Aluminum Silicates: chemistry / Glutaral:
chemistry / Humans / Microscopy, Atomic Force: methods /
Protein Multimerization / Protein Structure, Secondary /
Surface Properties / Time Factors / tau Proteins: chemistry
/ Aluminum Silicates (NLM Chemicals) / tau Proteins (NLM
Chemicals) / Glutaral (NLM Chemicals) / mica (NLM
Chemicals)},
cin = {AG (Eckhard) Mandelkow},
ddc = {570},
cid = {I:(DE-2719)1013014},
pnm = {342 - Disease Mechanisms and Model Systems (POF3-342)},
pid = {G:(DE-HGF)POF3-342},
typ = {PUB:(DE-HGF)3 / PUB:(DE-HGF)16},
pubmed = {pmid:22528090},
doi = {10.1007/978-1-61779-551-0_12},
url = {https://pub.dzne.de/record/141184},
}