%0 Journal Article
%A Alonso-Canovas, Araceli
%A Tembl Ferrairó, José Ignacio
%A Martínez-Torres, Irene
%A Lopez-Sendon Moreno, Jose Luis
%A Parees-Moreno, Isabel
%A Monreal-Laguillo, Enric
%A Pérez-Torre, Paula
%A Toledano Delgado, Rafael
%A García Ribas, Guillermo
%A Sastre Bataller, Isabel
%A Masjuan, Jaime
%A Martinez-Castrillo, Juan Carlos
%A Walter, Uwe
%T Transcranial sonography in atypical parkinsonism: How reliable is it in real clinical practice? A multicentre comprehensive study.
%J Parkinsonism & related disorders
%V 68
%@ 1353-8020
%C Amsterdam [u.a.]
%I Elsevier Science
%M DZNE-2020-07908
%P 40-45
%D 2019
%X Substantia nigra hyperechogenicity (SN+) in transcranial sonography (TCS) is frequent in Parkinson's disease (PD), while lenticular nucleus hyperechogenicity (LN+) and 3rd ventricle enlargement (3V+) are typical of Atypical Parkinsonisms (AP). However, there are no studies assessing the diagnostic yield of all TCS biomarkers in the three AP (progressive supranuclear palsy, PSP, multiple system atrophy, MSA, corticobasal degeneration, CBD). Previous references lack homogeneous criteria and data are incomprehensive.Analysis of TCS performed in routine clinical practice in AP and PD patients from two tertiary hospitals. Expert recommendations were strictly followed. Previous literature was critically analysed.155 AP (98 PSP, 40 MSA, 14 CBD), 254 PD, 145 control subjects were included. We confirmed good sensitivity for SN+ in PD (80
%K Aged
%K Aged, 80 and over
%K Corpus Striatum: diagnostic imaging
%K Female
%K Humans
%K Male
%K Middle Aged
%K Parkinsonian Disorders: diagnostic imaging
%K Reproducibility of Results
%K Sensitivity and Specificity
%K Substantia Nigra: diagnostic imaging
%K Third Ventricle: diagnostic imaging
%K Ultrasonography, Doppler, Transcranial: standards
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:31621617
%R 10.1016/j.parkreldis.2019.09.032
%U https://pub.dzne.de/record/141584