TY  - JOUR
AU  - Alonso-Canovas, Araceli
AU  - Tembl Ferrairó, José Ignacio
AU  - Martínez-Torres, Irene
AU  - Lopez-Sendon Moreno, Jose Luis
AU  - Parees-Moreno, Isabel
AU  - Monreal-Laguillo, Enric
AU  - Pérez-Torre, Paula
AU  - Toledano Delgado, Rafael
AU  - García Ribas, Guillermo
AU  - Sastre Bataller, Isabel
AU  - Masjuan, Jaime
AU  - Martinez-Castrillo, Juan Carlos
AU  - Walter, Uwe
TI  - Transcranial sonography in atypical parkinsonism: How reliable is it in real clinical practice? A multicentre comprehensive study.
JO  - Parkinsonism & related disorders
VL  - 68
SN  - 1353-8020
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - DZNE-2020-07908
SP  - 40-45
PY  - 2019
AB  - Substantia nigra hyperechogenicity (SN+) in transcranial sonography (TCS) is frequent in Parkinson's disease (PD), while lenticular nucleus hyperechogenicity (LN+) and 3rd ventricle enlargement (3V+) are typical of Atypical Parkinsonisms (AP). However, there are no studies assessing the diagnostic yield of all TCS biomarkers in the three AP (progressive supranuclear palsy, PSP, multiple system atrophy, MSA, corticobasal degeneration, CBD). Previous references lack homogeneous criteria and data are incomprehensive.Analysis of TCS performed in routine clinical practice in AP and PD patients from two tertiary hospitals. Expert recommendations were strictly followed. Previous literature was critically analysed.155 AP (98 PSP, 40 MSA, 14 CBD), 254 PD, 145 control subjects were included. We confirmed good sensitivity for SN+ in PD (80
KW  - Aged
KW  - Aged, 80 and over
KW  - Corpus Striatum: diagnostic imaging
KW  - Female
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Parkinsonian Disorders: diagnostic imaging
KW  - Reproducibility of Results
KW  - Sensitivity and Specificity
KW  - Substantia Nigra: diagnostic imaging
KW  - Third Ventricle: diagnostic imaging
KW  - Ultrasonography, Doppler, Transcranial: standards
LB  - PUB:(DE-HGF)16
C6  - pmid:31621617
DO  - DOI:10.1016/j.parkreldis.2019.09.032
UR  - https://pub.dzne.de/record/141584
ER  -