TY  - JOUR
AU  - Bainbridge, Wilma A
AU  - Berron, David
AU  - Schütze, Hartmut
AU  - Cardenas-Blanco, Arturo
AU  - Metzger, Coraline
AU  - Dobisch, Laura
AU  - Bittner, Daniel
AU  - Glanz, Wenzel
AU  - Spottke, Annika
AU  - Rudolph, Janna
AU  - Brosseron, Frederic
AU  - Bürger, Katharina
AU  - Janowitz, Daniel
AU  - Fliessbach, Klaus
AU  - Heneka, Michael
AU  - Laske, Christoph
AU  - Buchmann, Martina
AU  - Peters, Oliver
AU  - Diesing, Dominik
AU  - Li, Siyao
AU  - Priller, Josef
AU  - Spruth, Eike Jakob
AU  - Altenstein, Slawek
AU  - Schneider, Anja
AU  - Kofler, Barbara
AU  - Teipel, Stefan
AU  - Kilimann, Ingo
AU  - Wiltfang, Jens
AU  - Bartels, Claudia
AU  - Wolfsgruber, Steffen
AU  - Wagner, Michael
AU  - Jessen, Frank
AU  - Baker, Chris I
AU  - Düzel, Emrah
TI  - Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment.
JO  - Alzheimer's & dementia / Diagnosis, assessment & disease  monitoring
VL  - 11
IS  - 1
SN  - 2352-8729
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DZNE-2020-00387
SP  - 610-618
PY  - 2019
AB  - Impaired long-term memory is a defining feature of mild cognitive impairment (MCI). We tested whether this impairment is item specific, limited to some memoranda, whereas some remain consistently memorable.We conducted item-based analyses of long-term visual recognition memory. Three hundred ninety-four participants (healthy controls, subjective cognitive decline [SCD], and MCI) in the multicentric DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) were tested with images from a pool of 835 photographs.We observed consistent memorability for images in healthy controls, SCD, and MCI, predictable by a neural network trained on another healthy sample. Looking at memorability differences between groups, we identified images that could successfully categorize group membership with higher success and a substantial image reduction than the original image set.Individuals with SCD and MCI show consistent memorability for specific items, while other items show significant diagnosticity. Certain stimulus features could optimize diagnostic assessment, while others could support memory.
LB  - PUB:(DE-HGF)16
C6  - pmid:31517023
C2  - pmc:PMC6732671
DO  - DOI:10.1016/j.dadm.2019.07.005
UR  - https://pub.dzne.de/record/145027
ER  -