TY - JOUR
AU - Düzel, Emrah
AU - Acosta-Cabronero, Julio
AU - Berron, David
AU - Biessels, Geert Jan
AU - Björkman-Burtscher, Isabella
AU - Bottlaender, Michel
AU - Bowtell, Richard
AU - Buchem, Mark V
AU - Cardenas-Blanco, Arturo
AU - Boumezbeur, Fawzi
AU - Chan, Dennis
AU - Clare, Stuart
AU - Costagli, Mauro
AU - de Rochefort, Ludovic
AU - Fillmer, Ariane
AU - Gowland, Penny
AU - Hansson, Oskar
AU - Hendrikse, Jeroen
AU - Kraff, Oliver
AU - Ladd, Mark E
AU - Ronen, Itamar
AU - Petersen, Esben
AU - Rowe, James B
AU - Siebner, Hartwig
AU - Stöcker, Tony
AU - Straub, Sina
AU - Tosetti, Michela
AU - Uludag, Kamil
AU - Vignaud, Alexandre
AU - Zwanenburg, Jaco
AU - Speck, Oliver
TI - European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND).
JO - Alzheimer's & dementia / Diagnosis, assessment & disease monitoring
VL - 11
IS - 1
SN - 2352-8729
CY - Amsterdam [u.a.]
PB - Elsevier
M1 - DZNE-2020-00494
SP - 538-549
PY - 2019
AB - The goal of European Ultrahigh-Field Imaging Network in Neurodegenerative Diseases (EUFIND) is to identify opportunities and challenges of 7 Tesla (7T) MRI for clinical and research applications in neurodegeneration. EUFIND comprises 22 European and one US site, including over 50 MRI and dementia experts as well as neuroscientists.EUFIND combined consensus workshops and data sharing for multisite analysis, focusing on 7 core topics: clinical applications/clinical research, highest resolution anatomy, functional imaging, vascular systems/vascular pathology, iron mapping and neuropathology detection, spectroscopy, and quality assurance. Across these topics, EUFIND considered standard operating procedures, safety, and multivendor harmonization.The clinical and research opportunities and challenges of 7T MRI in each subtopic are set out as a roadmap. Specific MRI sequences for each subtopic were implemented in a pilot study presented in this report. Results show that a large multisite 7T imaging network with highly advanced and harmonized imaging sequences is feasible and may enable future multicentre ultrahigh-field MRI studies and clinical trials.The EUFIND network can be a major driver for advancing clinical neuroimaging research using 7T and for identifying use-cases for clinical applications in neurodegeneration.
LB - PUB:(DE-HGF)16
C6 - pmid:31388558
C2 - pmc:PMC6675944
DO - DOI:10.1016/j.dadm.2019.04.010
UR - https://pub.dzne.de/record/145135
ER -