%0 Conference Paper
%A Wieneke, Stephanie
%A Karl, Mike Oliver
%T Development of a human reporter stem cell line for mature cones in retinal organoids
%J Investigative ophthalmology & visual science
%V 59
%N 9
%@ 0146-0404
%M DZNE-2020-00617
%D 2018
%X Purpose : Much of our knowledge about photoreceptor development comes from the mouse retina that is rich in rods but has significantly lower amount of cones. The derivation of three-dimensional (3D) retinal organoids from human stem cells allowed us to study differentiation of human photoreceptors. Therefore, our aim was to develop a fluorescent reporter human induced pluripotent stem cell (hiPSC) line that would allow identification and isolation of postmitotic cones from 3D retinas and further transcriptomic analysis.
%B Annual Meeting of the Association for Research in Vision and Ophthalmology
%C 29 Apr 2018 - 3 May 2018, Honolulu, HI (USA)
Y2 29 Apr 2018 - 3 May 2018
M2 Honolulu, HI, USA
%F PUB:(DE-HGF)1 ; PUB:(DE-HGF)16
%9 AbstractJournal Article
%U https://pub.dzne.de/record/145260