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000145260 1001_ $$0P:(DE-2719)2812103$$aWieneke, Stephanie$$b0$$udzne
000145260 1112_ $$aAnnual Meeting of the Association for Research in Vision and Ophthalmology$$cHonolulu, HI$$d2018-04-29 - 2018-05-03$$gARVO$$wUSA
000145260 245__ $$aDevelopment of a human reporter stem cell line for mature cones in retinal organoids
000145260 260__ $$c2018
000145260 3367_ $$0PUB:(DE-HGF)1$$2PUB:(DE-HGF)$$aAbstract$$babstract$$mabstract$$s1714044996_4335
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000145260 520__ $$aPurpose : Much of our knowledge about photoreceptor development comes from the mouse retina that is rich in rods but has significantly lower amount of cones. The derivation of three-dimensional (3D) retinal organoids from human stem cells allowed us to study differentiation of human photoreceptors. Therefore, our aim was to develop a fluorescent reporter human induced pluripotent stem cell (hiPSC) line that would allow identification and isolation of postmitotic cones from 3D retinas and further transcriptomic analysis.
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000145260 7001_ $$0P:(DE-2719)2000041$$aKarl, Mike Oliver$$b1$$eLast author$$udzne
000145260 773__ $$0PERI:(DE-600)2009858-3$$n9$$tInvestigative ophthalmology & visual science$$v59$$x0146-0404$$y2018
000145260 8564_ $$uhttps://iovs.arvojournals.org/article.aspx?articleid=2691050
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