TY  - CONF
AU  - Wieneke, Stephanie
AU  - Karl, Mike Oliver
TI  - Development of a human reporter stem cell line for mature cones in retinal organoids
JO  - Investigative ophthalmology & visual science
VL  - 59
IS  - 9
SN  - 0146-0404
M1  - DZNE-2020-00617
PY  - 2018
AB  - Purpose : Much of our knowledge about photoreceptor development comes from the mouse retina that is rich in rods but has significantly lower amount of cones. The derivation of three-dimensional (3D) retinal organoids from human stem cells allowed us to study differentiation of human photoreceptors. Therefore, our aim was to develop a fluorescent reporter human induced pluripotent stem cell (hiPSC) line that would allow identification and isolation of postmitotic cones from 3D retinas and further transcriptomic analysis.
T2  - Annual Meeting of the Association for Research in Vision and Ophthalmology
CY  - 29 Apr 2018 - 3 May 2018, Honolulu, HI (USA)
Y2  - 29 Apr 2018 - 3 May 2018
M2  - Honolulu, HI, USA
LB  - PUB:(DE-HGF)1 ; PUB:(DE-HGF)16
UR  - https://pub.dzne.de/record/145260
ER  -