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@INPROCEEDINGS{Engelhardt:145574,
author = {Engelhardt, Jakob},
title = {{W}01-5: {I}nfluence of auxiliary subunits on {AMPAR}
function in hippo-campus and thalamus},
journal = {Acta physiologica},
volume = {216},
number = {S707},
issn = {0001-6772},
reportid = {DZNE-2020-00907},
pages = {Workshop 1},
year = {2016},
abstract = {Auxiliary subunits modulate function, surface trafficking
and subcellular localization of AMPA receptors. I will
present data from our laboratory on how we investigate the
func-tion of auxiliary subunits of the CKAMP and TARP
families in heterologous expression systems, acute brain
slices and in vivo. Number and properties of synaptic and
extrasynaptic AMPA receptors in dentate gyrus granule cells
and lateral geniculate relay neurons are strongly
influenced by the inter-action with CKAMP44 and TARP y-8.
Moreover, these two auxiliary subunits affect synaptic
short-term and long-term plasticity. Finally, tetrode
recordings from non-anaesthetized mice revealed that
auxiliary proteins change the activity of neurons by
modulating the integration of excitatory inputs.},
month = {Mar},
date = {2016-03-03},
organization = {95th Annual Meeting of the German
Physiological Society, Lübeck
(Germany), 3 Mar 2016 - 5 Mar 2016},
cin = {AG Engelhardt},
ddc = {610},
cid = {I:(DE-2719)1013023},
pnm = {341 - Molecular Signaling (POF3-341)},
pid = {G:(DE-HGF)POF3-341},
typ = {PUB:(DE-HGF)1 / PUB:(DE-HGF)16},
url = {https://pub.dzne.de/record/145574},
}