TY  - CONF
AU  - Fell, Juergen
AU  - Wagner, Tobias
AU  - Staresina, Bernhard P.
AU  - Ranganath, Charan
AU  - Elger, Christian E.
AU  - Axmacher, Nikolai
TI  - Rhinal-Hippocampal Information Flow Reverses Between Memory Encoding and Retrieval
VL  - 9947
CY  - Cham
PB  - Springer International Publishing
M1  - DZNE-2020-00945
SN  - 978-3-319-46686-6 (print)
T2  - Lecture Notes in Computer Science
SP  - 105-114
PY  - 2016
AB  - The medial temporal lobe is crucial for the encoding and retrieval of episodic long-term memories. It is widely assumed that memory encoding is associated with information transfer from sensory regions via the rhinal cortex into the hippocampus. Retrieval of information should then be associated with transfer in the reverse direction. However, experimental evidence for this mechanism is still lacking. Here, we show in human intracranial EEG data during two independent recognition memory paradigms that rhinal-hippocampal information flow significantly changes its directionality from encoding to retrieval. Using a novel phase-based method to analyze directional coupling of oscillations, coupling values were more positive (i.e., from rhinal cortex to the hippocampus) during encoding as compared to retrieval. These effects were observed in the delta (1–3 Hz) range where rhinal-hippocampal post-stimulus phase synchronization increased most robustly across both experiments.
T2  - 23rd International Conference on Neural Information Processing ICONIP 2016: Neural Information Processing
CY  - 16 Oct 2016 - 21 Oct 2016, Kyoto (Japan)
Y2  - 16 Oct 2016 - 21 Oct 2016
M2  - Kyoto, Japan
LB  - PUB:(DE-HGF)8 ; PUB:(DE-HGF)7
DO  - DOI:10.1007/978-3-319-46687-3_11
UR  - https://pub.dzne.de/record/145615
ER  -