TY  - CONF
AU  - Schultz, Stephanie
AU  - Adedokun, Adedamola
AU  - Strain, Jeremy
AU  - Wang, Qing
AU  - Preische, Oliver
AU  - Kuhle, Jens
AU  - Morris, John
AU  - Bateman, Randall
AU  - Jucker, Mathias
AU  - Benzinger, Tammie
AU  - Gordon, Brian
TI  - M148. Association between Serum Neurofilament Lightand Established White Matter Neuroimaging Markers inAutosomal Dominant Alzheimer Disease
JO  - Annals of neurology
VL  - 86
IS  - S23
SN  - 0364-5134
M1  - DZNE-2020-01022
SP  - S145 - S146
PY  - 2019
AB  - Background: White matter (WM) alterations are a commonfeature of Alzheimer Disease (AD), typically detected in vivowith diffusion tensor imaging (DTI). Blood-based neurofila-ment light (NfL) is an emerging biomarker for monitoringneurodegeneration. While NfL is thought to reflect damageto myelinated axons, minimal work has directly examinedthis association. The objective of this study was to examinethe cross-sectional and longitudinal relationship betweenWM neuroimaging markers and serum NfL levels.
T2  - 144th Annual Meeting American Neurological Association
CY  - 13 Oct 2019 - 15 Oct 2019, St. Louis, Mo (USA)
Y2  - 13 Oct 2019 - 15 Oct 2019
M2  - St. Louis, Mo, USA
LB  - PUB:(DE-HGF)1 ; PUB:(DE-HGF)16
UR  - https://pub.dzne.de/record/145737
ER  -