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@INPROCEEDINGS{Schultz:145737,
author = {Schultz, Stephanie and Adedokun, Adedamola and Strain,
Jeremy and Wang, Qing and Preische, Oliver and Kuhle, Jens
and Morris, John and Bateman, Randall and Jucker, Mathias
and Benzinger, Tammie and Gordon, Brian},
title = {{M}148. {A}ssociation between {S}erum {N}eurofilament
{L}ightand {E}stablished {W}hite {M}atter {N}euroimaging
{M}arkers in{A}utosomal {D}ominant {A}lzheimer {D}isease},
journal = {Annals of neurology},
volume = {86},
number = {S23},
issn = {0364-5134},
reportid = {DZNE-2020-01022},
pages = {S145 - S146},
year = {2019},
abstract = {Background: White matter (WM) alterations are a
commonfeature of Alzheimer Disease (AD), typically detected
in vivowith diffusion tensor imaging (DTI). Blood-based
neurofila-ment light (NfL) is an emerging biomarker for
monitoringneurodegeneration. While NfL is thought to
reflect damageto myelinated axons, minimal work has
directly examinedthis association. The objective of this
study was to examinethe cross-sectional and longitudinal
relationship betweenWM neuroimaging markers and serum NfL
levels.},
month = {Oct},
date = {2019-10-13},
organization = {144th Annual Meeting American
Neurological Association, St. Louis, Mo
(USA), 13 Oct 2019 - 15 Oct 2019},
cin = {AG Jucker},
ddc = {610},
cid = {I:(DE-2719)1210001},
pnm = {342 - Disease Mechanisms and Model Systems (POF3-342)},
pid = {G:(DE-HGF)POF3-342},
typ = {PUB:(DE-HGF)1 / PUB:(DE-HGF)16},
url = {https://pub.dzne.de/record/145737},
}