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100 1 _ |a Schultz, Stephanie
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111 2 _ |a 144th Annual Meeting American Neurological Association
|g ANA 2019
|c St. Louis, Mo
|d 2019-10-13 - 2019-10-15
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245 _ _ |a M148. Association between Serum Neurofilament Lightand Established White Matter Neuroimaging Markers inAutosomal Dominant Alzheimer Disease
260 _ _ |c 2019
336 7 _ |a Abstract
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520 _ _ |a Background: White matter (WM) alterations are a commonfeature of Alzheimer Disease (AD), typically detected in vivowith diffusion tensor imaging (DTI). Blood-based neurofila-ment light (NfL) is an emerging biomarker for monitoringneurodegeneration. While NfL is thought to reflect damageto myelinated axons, minimal work has directly examinedthis association. The objective of this study was to examinethe cross-sectional and longitudinal relationship betweenWM neuroimaging markers and serum NfL levels.
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700 1 _ |a Adedokun, Adedamola
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700 1 _ |a Strain, Jeremy
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700 1 _ |a Wang, Qing
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700 1 _ |a Preische, Oliver
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700 1 _ |a Kuhle, Jens
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700 1 _ |a Morris, John
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700 1 _ |a Bateman, Randall
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700 1 _ |a Jucker, Mathias
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700 1 _ |a Benzinger, Tammie
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700 1 _ |a Gordon, Brian
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773 _ _ |0 PERI:(DE-600)2037912-2
|n S23
|p S145 - S146
|t Annals of neurology
|v 86
|y 2019
|x 0364-5134
856 4 _ |u https://onlinelibrary.wiley.com/doi/epdf/10.1002/ana.25587
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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