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@ARTICLE{Sulzer:154040,
      author       = {Sulzer, Patricia and Liebig, Luise and Csoti, Ilona and
                      Graessel, Elmar and Wurster, Isabel and Berg, Daniela and
                      Liepelt-Scarfone, Inga},
      title        = {{A} time-efficient screening tool for activities of daily
                      living functions in {P}arkinson’s disease dementia},
      journal      = {Journal of clinical and experimental neuropsychology},
      volume       = {42},
      number       = {8},
      issn         = {1744-411X},
      address      = {Abingdon},
      publisher    = {Routledge, Taylor $\&$ Francis Group86092},
      reportid     = {DZNE-2021-00022},
      pages        = {867 - 879},
      year         = {2020},
      abstract     = {InstructionIn Parkinson’s disease (PD), activities of
                      daily living (ADL) impairments are crucial for diagnosis of
                      dementia (PDD). Performance-based tests are promising tools
                      to discriminate between different levels of cognitive
                      impairment in PD; however, the value of those tests for
                      diagnosis of PDD is only sparsely investigated. Therefore,
                      we evaluated the Erlangen Test of Activities of Daily Living
                      (E-ADL), a time-efficient performance-based ADL test, in
                      PD.MethodIn this cross-sectional study, 40 PD patients with
                      normal cognition (PD-NC), 45 patients with mild cognitive
                      impairment (PD-MCI) and 21 patients with PDD were assessed
                      with a comprehensive ADL and cognitive test
                      battery.ResultsInterrater reliability (rs =.86) indicated
                      high consistency of the standardized E-ADL scoring system
                      between raters. The E-ADL correlated significantly with
                      other tests of ADL functions (p <.01), highest with an
                      alternative performance-based ADL test (rs = −.52), and
                      lowest with self-ratings and a physician-rated scale. The
                      E-ADL was also associated with cognitive impairment (p
                      <.01), but also with motor impairment. A binary logistic
                      regression model verified that the E-ADL (p =.04) was an
                      independent predictor of PDD, in addition to motor
                      impairment explaining $53.3\%$ of variance. Receiver
                      operating characteristic curve analysis of the E-ADL
                      revealed an area under the curve of 0.78, a specificity of
                      $77\%,$ and a sensitivity of $67\%$ for diagnosis
                      PDD.ConclusionsThe standardized, easy, and quick to
                      administer E-ADL showed acceptable levels of reliability,
                      and validity in PD and measures cognitive-driven ADL
                      functions. Therefore, it might be a suitable test to support
                      diagnosis of PDD in the clinical daily routine.},
      keywords     = {Activities of Daily Living: psychology / Aged / Aged, 80
                      and over / Cognitive Dysfunction: diagnosis / Cognitive
                      Dysfunction: etiology / Cognitive Dysfunction: psychology /
                      Cross-Sectional Studies / Dementia: diagnosis / Dementia:
                      etiology / Dementia: psychology / Female / Humans / Male /
                      Middle Aged / Motor Skills / Neuropsychological Tests /
                      Parkinson Disease: complications / Parkinson Disease:
                      diagnosis / Parkinson Disease: psychology / ROC Curve / Self
                      Concept / Sensitivity and Specificity},
      cin          = {AG Gasser 1 / Biobanking Facility Tübingen},
      ddc          = {610},
      cid          = {I:(DE-2719)1210000 / I:(DE-2719)1240004},
      pnm          = {345 - Population Studies and Genetics (POF3-345)},
      pid          = {G:(DE-HGF)POF3-345},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33043797},
      doi          = {10.1080/13803395.2020.1825634},
      url          = {https://pub.dzne.de/record/154040},
}