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024 7 _ |a 10.1080/13803395.2020.1825634
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024 7 _ |a 0168-8634
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024 7 _ |a 1380-3395
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024 7 _ |a 1744-411X
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037 _ _ |a DZNE-2021-00022
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Sulzer, Patricia
|0 P:(DE-2719)2811919
|b 0
|e First author
245 _ _ |a A time-efficient screening tool for activities of daily living functions in Parkinson’s disease dementia
260 _ _ |a Abingdon
|c 2020
|b Routledge, Taylor & Francis Group86092
336 7 _ |a article
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520 _ _ |a InstructionIn Parkinson’s disease (PD), activities of daily living (ADL) impairments are crucial for diagnosis of dementia (PDD). Performance-based tests are promising tools to discriminate between different levels of cognitive impairment in PD; however, the value of those tests for diagnosis of PDD is only sparsely investigated. Therefore, we evaluated the Erlangen Test of Activities of Daily Living (E-ADL), a time-efficient performance-based ADL test, in PD.MethodIn this cross-sectional study, 40 PD patients with normal cognition (PD-NC), 45 patients with mild cognitive impairment (PD-MCI) and 21 patients with PDD were assessed with a comprehensive ADL and cognitive test battery.ResultsInterrater reliability (rs =.86) indicated high consistency of the standardized E-ADL scoring system between raters. The E-ADL correlated significantly with other tests of ADL functions (p <.01), highest with an alternative performance-based ADL test (rs = −.52), and lowest with self-ratings and a physician-rated scale. The E-ADL was also associated with cognitive impairment (p <.01), but also with motor impairment. A binary logistic regression model verified that the E-ADL (p =.04) was an independent predictor of PDD, in addition to motor impairment explaining 53.3% of variance. Receiver operating characteristic curve analysis of the E-ADL revealed an area under the curve of 0.78, a specificity of 77%, and a sensitivity of 67% for diagnosis PDD.ConclusionsThe standardized, easy, and quick to administer E-ADL showed acceptable levels of reliability, and validity in PD and measures cognitive-driven ADL functions. Therefore, it might be a suitable test to support diagnosis of PDD in the clinical daily routine.
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650 _ 2 |a Activities of Daily Living: psychology
|2 MeSH
650 _ 2 |a Aged
|2 MeSH
650 _ 2 |a Aged, 80 and over
|2 MeSH
650 _ 2 |a Cognitive Dysfunction: diagnosis
|2 MeSH
650 _ 2 |a Cognitive Dysfunction: etiology
|2 MeSH
650 _ 2 |a Cognitive Dysfunction: psychology
|2 MeSH
650 _ 2 |a Cross-Sectional Studies
|2 MeSH
650 _ 2 |a Dementia: diagnosis
|2 MeSH
650 _ 2 |a Dementia: etiology
|2 MeSH
650 _ 2 |a Dementia: psychology
|2 MeSH
650 _ 2 |a Female
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Male
|2 MeSH
650 _ 2 |a Middle Aged
|2 MeSH
650 _ 2 |a Motor Skills
|2 MeSH
650 _ 2 |a Neuropsychological Tests
|2 MeSH
650 _ 2 |a Parkinson Disease: complications
|2 MeSH
650 _ 2 |a Parkinson Disease: diagnosis
|2 MeSH
650 _ 2 |a Parkinson Disease: psychology
|2 MeSH
650 _ 2 |a ROC Curve
|2 MeSH
650 _ 2 |a Self Concept
|2 MeSH
650 _ 2 |a Sensitivity and Specificity
|2 MeSH
700 1 _ |a Liebig, Luise
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700 1 _ |a Csoti, Ilona
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700 1 _ |a Graessel, Elmar
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700 1 _ |a Wurster, Isabel
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700 1 _ |a Berg, Daniela
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700 1 _ |a Liepelt-Scarfone, Inga
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773 _ _ |a 10.1080/13803395.2020.1825634
|g Vol. 42, no. 8, p. 867 - 879
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Marc 21