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000154381 1001_ $$0P:(DE-2719)9001492$$aWesselmann, Linda$$b0$$eFirst author$$udzne
000154381 245__ $$aDietary patterns are related to cognitive functioning in elderly enriched with individuals at increased risk for Alzheimer's disease.
000154381 260__ $$aHeidelberg$$bSpringer$$c2021
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000154381 520__ $$aTo investigate cross-sectional associations between dietary patterns and cognitive functioning in elderly free of dementia.Data of 389 participants from the German DELCODE study (52% female, 69 ± 6 years, mean Mini Mental State Score 29 ± 1) were included. The sample was enriched with elderly at increased risk for Alzheimer's disease (AD) by including participants with subjective cognitive decline, mild cognitive impairment (MCI) and siblings of AD patients. Mediterranean and MIND diets were derived from 148 Food Frequency Questionnaire items, and data-driven patterns by principal component analysis (PCA) of 39 food groups. Associations between dietary patterns and five cognitive domain scores were analyzed with linear regression analyses adjusted for demographics (model 1), and additionally for energy intake, BMI, other lifestyle variables and APOe4-status (model 2). For PCA-derived dietary components, final model 3 included all other dietary components.In fully adjusted models, adherence to Mediterranean and MIND diet was associated with better memory. The 'alcoholic beverages' PCA component was positively associated with most cognitive domains. Exclusion of MCI subjects (n = 60) revealed that Mediterranean and MIND diet were also related to language functions; associations with the alcoholic beverages component were attenuated, but most remained significant.In line with data from elderly population samples, Mediterranean and MIND diet and some data-derived dietary patterns were related to memory and language function. Longitudinal data are needed to draw conclusions on the putative effect of nutrition on the rate of cognitive decline, and on the potential of dietary interventions in groups at increased risk for AD.
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000154381 650_7 $$2Other$$aCognition
000154381 650_7 $$2Other$$aDementia
000154381 650_7 $$2Other$$aDietary patterns
000154381 650_7 $$2Other$$aMIND diet
000154381 650_7 $$2Other$$aMediterranean diet
000154381 650_2 $$2MeSH$$aAged
000154381 650_2 $$2MeSH$$aAlzheimer Disease: epidemiology
000154381 650_2 $$2MeSH$$aCognition
000154381 650_2 $$2MeSH$$aCognitive Dysfunction: epidemiology
000154381 650_2 $$2MeSH$$aCognitive Dysfunction: etiology
000154381 650_2 $$2MeSH$$aCross-Sectional Studies
000154381 650_2 $$2MeSH$$aDiet, Mediterranean
000154381 650_2 $$2MeSH$$aFemale
000154381 650_2 $$2MeSH$$aHumans
000154381 650_2 $$2MeSH$$aMale
000154381 693__ $$0EXP:(DE-2719)DELCODE-20140101$$5EXP:(DE-2719)DELCODE-20140101$$eLongitudinal Cognitive Impairment and Dementia Study$$x0
000154381 7001_ $$0P:(DE-2719)2811697$$aMelo van Lent, Debora$$b1
000154381 7001_ $$0P:(DE-2719)2813830$$aSchröder, A.$$b2
000154381 7001_ $$0P:(DE-HGF)0$$avan de Rest, O.$$b3
000154381 7001_ $$0P:(DE-2719)2811024$$aPeters, O.$$b4
000154381 7001_ $$0P:(DE-HGF)0$$aMenne, F.$$b5
000154381 7001_ $$0P:(DE-HGF)0$$aFuentes, M.$$b6
000154381 7001_ $$0P:(DE-2719)2811122$$aPriller, J.$$b7
000154381 7001_ $$0P:(DE-2719)2812446$$aSpruth, E. J.$$b8
000154381 7001_ $$0P:(DE-HGF)0$$aAltenstein, S.$$b9
000154381 7001_ $$0P:(DE-2719)2812035$$aSchneider, A.$$b10
000154381 7001_ $$0P:(DE-2719)2811326$$aFließbach, K.$$b11
000154381 7001_ $$0P:(DE-2719)2810395$$aRoeske, S.$$b12
000154381 7001_ $$0P:(DE-2719)2810544$$aWolfsgruber, S.$$b13
000154381 7001_ $$0P:(DE-2719)2812139$$aKleineidam, L.$$b14
000154381 7001_ $$0P:(DE-2719)2811324$$aSpottke, A.$$b15
000154381 7001_ $$0P:(DE-HGF)0$$aPross, V.$$b16
000154381 7001_ $$0P:(DE-2719)2811317$$aWiltfang, J.$$b17
000154381 7001_ $$0P:(DE-2719)9001493$$aVukovich, Ruth C.$$b18$$udzne
000154381 7001_ $$0P:(DE-2719)9001495$$aSchild, Ann Katrin$$b19$$udzne
000154381 7001_ $$0P:(DE-2719)2000005$$aDüzel, E.$$b20
000154381 7001_ $$0P:(DE-2719)9000443$$aMetzger, Coraline$$b21
000154381 7001_ $$0P:(DE-2719)2811614$$aGlanz, W.$$b22
000154381 7001_ $$0P:(DE-2719)2811351$$aBürger, Katharina$$b23
000154381 7001_ $$0P:(DE-HGF)0$$aJanowitz, D.$$b24
000154381 7001_ $$0P:(DE-2719)2812234$$aPerneczky, R.$$b25
000154381 7001_ $$0P:(DE-2719)9001496$$aTatò, M.$$b26$$udzne
000154381 7001_ $$0P:(DE-2719)2000026$$aTeipel, S.$$b27
000154381 7001_ $$0P:(DE-2719)2810394$$aKilimann, I.$$b28
000154381 7001_ $$0P:(DE-2719)2000055$$aLaske, C.$$b29
000154381 7001_ $$0P:(DE-2719)9000383$$aBuchmann, M.$$b30
000154381 7001_ $$0P:(DE-HGF)0$$aRamirez, A.$$b31
000154381 7001_ $$0P:(DE-HGF)0$$aSikkes, S. A. M.$$b32
000154381 7001_ $$0P:(DE-2719)2000032$$aJessen, F.$$b33
000154381 7001_ $$0P:(DE-HGF)0$$avan der Flier, W. M.$$b34
000154381 7001_ $$0P:(DE-2719)2000057$$aWagner, Michael$$b35$$eLast author
000154381 773__ $$0PERI:(DE-600)1463312-7$$a10.1007/s00394-020-02257-6$$gVol. 60, no. 2, p. 849 - 860$$n2$$p849 - 860$$tEuropean journal of nutrition$$v60$$x1436-6215$$y2021
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