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@ARTICLE{Wesselmann:154381,
      author       = {Wesselmann, Linda and Melo van Lent, Debora and Schröder,
                      A. and van de Rest, O. and Peters, O. and Menne, F. and
                      Fuentes, M. and Priller, J. and Spruth, E. J. and
                      Altenstein, S. and Schneider, A. and Fließbach, K. and
                      Roeske, S. and Wolfsgruber, S. and Kleineidam, L. and
                      Spottke, A. and Pross, V. and Wiltfang, J. and Vukovich,
                      Ruth C. and Schild, Ann Katrin and Düzel, E. and Metzger,
                      Coraline and Glanz, W. and Bürger, Katharina and Janowitz,
                      D. and Perneczky, R. and Tatò, M. and Teipel, S. and
                      Kilimann, I. and Laske, C. and Buchmann, M. and Ramirez, A.
                      and Sikkes, S. A. M. and Jessen, F. and van der Flier, W. M.
                      and Wagner, Michael},
      title        = {{D}ietary patterns are related to cognitive functioning in
                      elderly enriched with individuals at increased risk for
                      {A}lzheimer's disease.},
      journal      = {European journal of nutrition},
      volume       = {60},
      number       = {2},
      issn         = {1436-6215},
      address      = {Heidelberg},
      publisher    = {Springer},
      reportid     = {DZNE-2021-00234},
      pages        = {849 - 860},
      year         = {2021},
      note         = {ISSN 1436-6215 not unique: **3 hits**.},
      abstract     = {To investigate cross-sectional associations between dietary
                      patterns and cognitive functioning in elderly free of
                      dementia.Data of 389 participants from the German DELCODE
                      study $(52\%$ female, 69 ± 6 years, mean Mini Mental State
                      Score 29 ± 1) were included. The sample was enriched with
                      elderly at increased risk for Alzheimer's disease (AD) by
                      including participants with subjective cognitive decline,
                      mild cognitive impairment (MCI) and siblings of AD patients.
                      Mediterranean and MIND diets were derived from 148 Food
                      Frequency Questionnaire items, and data-driven patterns by
                      principal component analysis (PCA) of 39 food groups.
                      Associations between dietary patterns and five cognitive
                      domain scores were analyzed with linear regression analyses
                      adjusted for demographics (model 1), and additionally for
                      energy intake, BMI, other lifestyle variables and
                      APOe4-status (model 2). For PCA-derived dietary components,
                      final model 3 included all other dietary components.In fully
                      adjusted models, adherence to Mediterranean and MIND diet
                      was associated with better memory. The 'alcoholic beverages'
                      PCA component was positively associated with most cognitive
                      domains. Exclusion of MCI subjects (n = 60) revealed that
                      Mediterranean and MIND diet were also related to language
                      functions; associations with the alcoholic beverages
                      component were attenuated, but most remained significant.In
                      line with data from elderly population samples,
                      Mediterranean and MIND diet and some data-derived dietary
                      patterns were related to memory and language function.
                      Longitudinal data are needed to draw conclusions on the
                      putative effect of nutrition on the rate of cognitive
                      decline, and on the potential of dietary interventions in
                      groups at increased risk for AD.},
      keywords     = {Aged / Alzheimer Disease: epidemiology / Cognition /
                      Cognitive Dysfunction: epidemiology / Cognitive Dysfunction:
                      etiology / Cross-Sectional Studies / Diet, Mediterranean /
                      Female / Humans / Male / Cognition (Other) / Dementia
                      (Other) / Dietary patterns (Other) / MIND diet (Other) /
                      Mediterranean diet (Other)},
      cin          = {AG Priller / Clinical Dementia Research Bonn / Patient
                      Studies Bonn / AG Wagner / AG Wiltfang / AG Höglinger 1 /
                      AG Düzel / AG Levin / AG Teipel / AG Jucker / Tübingen
                      common / Delcode},
      ddc          = {610},
      cid          = {I:(DE-2719)5000007 / I:(DE-2719)1011305 /
                      I:(DE-2719)1011101 / I:(DE-2719)1011201 / I:(DE-2719)1410006
                      / I:(DE-2719)1110002 / I:(DE-2719)5000006 /
                      I:(DE-2719)1111016 / I:(DE-2719)1510100 / I:(DE-2719)1210001
                      / I:(DE-2719)6000018 / I:(DE-2719)5000034},
      pnm          = {353 - Clinical and Health Care Research (POF4-353) / 352 -
                      Disease Mechanisms (POF4-352)},
      pid          = {G:(DE-HGF)POF4-353 / G:(DE-HGF)POF4-352},
      experiment   = {EXP:(DE-2719)DELCODE-20140101},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:32472387},
      pmc          = {pmc:PMC7900077},
      doi          = {10.1007/s00394-020-02257-6},
      url          = {https://pub.dzne.de/record/154381},
}