TY  - JOUR
AU  - Schmüdderich, Kathrin
AU  - Holle, Daniela
AU  - Ströbel, Armin
AU  - Holle, Bernhard
AU  - Palm, Rebecca
TI  - Relationship between the severity of agitation and quality of life in residents with dementia living in German nursing homes - a secondary data analysis.
JO  - BMC psychiatry
VL  - 21
IS  - 1
SN  - 1471-244X
CY  - Heidelberg
PB  - Springer
M1  - DZNE-2021-00722
SP  - 191
PY  - 2021
AB  - Severe agitation and its relation to single dimensions of quality of life are not well understood. The aim of this study was to gain more knowledge about severe agitation and to examine the relationships between the severity of agitation and single dimensions of quality of life among residents with dementia living in German nursing homes.This exploratory secondary analysis included data from 1947 residents of 66 German nursing homes from the DemenzMonitor study. The construct of agitation was defined as a composite score of the items agitation/aggression, irritability/lability and disinhibition from the Neuropsychiatric Inventory Questionnaire (NPI-Q); the resident was classified as severely agitated if at least one of these symptoms was rated as 'severe'. The single dimensions of quality of life were measured with the short version of the QUALIDEM instrument. To avoid selection bias, two controls with mild or no agitation were selected for each resident with severe agitation using propensity score matching. Mixed linear regression models were then generated to determine the differences in the dimensions of quality of life for the severity of agitation and the defining items.For four out of five dimensions of quality of life of the short version of QUALIDEM, residents with severe agitation had significantly lower values than residents without severe agitation. Converted to scale size, the greatest difference between both groups was found in the dimension social isolation with 23.0
KW  - Aggression
KW  - Data Analysis
KW  - Dementia: complications
KW  - Humans
KW  - Nursing Homes
KW  - Psychomotor Agitation
KW  - Quality of Life
KW  - Aggression (Other)
KW  - Agitation (Other)
KW  - Dementia (Other)
KW  - Nursing home (Other)
KW  - Quality of life (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:33849487
C2  - pmc:PMC8042694
DO  - DOI:10.1186/s12888-021-03167-5
UR  - https://pub.dzne.de/record/155544
ER  -