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000155556 0247_ $$2doi$$a10.1161/STROKEAHA.120.031742
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000155556 037__ $$aDZNE-2021-00734
000155556 041__ $$aEnglish
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000155556 1001_ $$aLo, Eng H$$b0
000155556 245__ $$aCircadian Biology and Stroke.
000155556 260__ $$aPhiladelphia, Pa.$$bLippincott Williams & Wilkins$$c2021
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000155556 520__ $$aCircadian biology modulates almost all aspects of mammalian physiology, disease, and response to therapies. Emerging data suggest that circadian biology may significantly affect the mechanisms of susceptibility, injury, recovery, and the response to therapy in stroke. In this review/perspective, we survey the accumulating literature and attempt to connect molecular, cellular, and physiological pathways in circadian biology to clinical consequences in stroke. Accounting for the complex and multifactorial effects of circadian rhythm may improve translational opportunities for stroke diagnostics and therapeutics.
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000155556 650_7 $$2Other$$abiomarkers
000155556 650_7 $$2Other$$acircadian rhythm
000155556 650_7 $$2Other$$aimmune system
000155556 650_7 $$2Other$$aischemia
000155556 650_7 $$2Other$$aneuroprotection
000155556 650_7 $$2Other$$asleep
000155556 650_2 $$2MeSH$$aAnimals
000155556 650_2 $$2MeSH$$aCircadian Rhythm: physiology
000155556 650_2 $$2MeSH$$aClinical Trials as Topic: methods
000155556 650_2 $$2MeSH$$aHumans
000155556 650_2 $$2MeSH$$aInflammation Mediators: physiology
000155556 650_2 $$2MeSH$$aNeurovascular Coupling: physiology
000155556 650_2 $$2MeSH$$aStroke: diagnosis
000155556 650_2 $$2MeSH$$aStroke: physiopathology
000155556 650_2 $$2MeSH$$aStroke: therapy
000155556 7001_ $$aAlbers, Gregory W$$b1
000155556 7001_ $$0P:(DE-2719)2000030$$aDichgans, Martin$$b2$$udzne
000155556 7001_ $$aDonnan, Geoffrey$$b3
000155556 7001_ $$aEsposito, Elga$$b4
000155556 7001_ $$aFoster, Russell$$b5
000155556 7001_ $$aHowells, David W$$b6
000155556 7001_ $$aHuang, Yi-Ge$$b7
000155556 7001_ $$aJi, Xunming$$b8
000155556 7001_ $$aKlerman, Elizabeth B$$b9
000155556 7001_ $$aLee, Sarah$$b10
000155556 7001_ $$aLi, Wenlu$$b11
000155556 7001_ $$aLiebeskind, David S$$b12
000155556 7001_ $$aLizasoain, Ignacio$$b13
000155556 7001_ $$aMandeville, Emiri T$$b14
000155556 7001_ $$aMoro, Maria A$$b15
000155556 7001_ $$aNing, MingMing$$b16
000155556 7001_ $$aRay, David$$b17
000155556 7001_ $$aSakadžić, Sava$$b18
000155556 7001_ $$aSaver, Jeffrey L$$b19
000155556 7001_ $$aScheer, Frank A J L$$b20
000155556 7001_ $$aSelim, Magdy$$b21
000155556 7001_ $$aTiedt, Steffen$$b22
000155556 7001_ $$aZhang, Fang$$b23
000155556 7001_ $$aBuchan, Alastair M$$b24
000155556 773__ $$0PERI:(DE-600)1467823-8$$a10.1161/STROKEAHA.120.031742$$gVol. 52, no. 6, p. 2180 - 2190$$n6$$p2180 - 2190$$tStroke$$v52$$x1524-4628$$y2021
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