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001     155556
005     20230915092328.0
024 7 _ |a 10.1161/STROKEAHA.120.031742
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024 7 _ |a pmid:33940951
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024 7 _ |a 0039-2499
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024 7 _ |a 1524-4628
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037 _ _ |a DZNE-2021-00734
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Lo, Eng H
|b 0
245 _ _ |a Circadian Biology and Stroke.
260 _ _ |a Philadelphia, Pa.
|c 2021
|b Lippincott Williams & Wilkins
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520 _ _ |a Circadian biology modulates almost all aspects of mammalian physiology, disease, and response to therapies. Emerging data suggest that circadian biology may significantly affect the mechanisms of susceptibility, injury, recovery, and the response to therapy in stroke. In this review/perspective, we survey the accumulating literature and attempt to connect molecular, cellular, and physiological pathways in circadian biology to clinical consequences in stroke. Accounting for the complex and multifactorial effects of circadian rhythm may improve translational opportunities for stroke diagnostics and therapeutics.
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650 _ 7 |a biomarkers
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650 _ 7 |a circadian rhythm
|2 Other
650 _ 7 |a immune system
|2 Other
650 _ 7 |a ischemia
|2 Other
650 _ 7 |a neuroprotection
|2 Other
650 _ 7 |a sleep
|2 Other
650 _ 2 |a Animals
|2 MeSH
650 _ 2 |a Circadian Rhythm: physiology
|2 MeSH
650 _ 2 |a Clinical Trials as Topic: methods
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Inflammation Mediators: physiology
|2 MeSH
650 _ 2 |a Neurovascular Coupling: physiology
|2 MeSH
650 _ 2 |a Stroke: diagnosis
|2 MeSH
650 _ 2 |a Stroke: physiopathology
|2 MeSH
650 _ 2 |a Stroke: therapy
|2 MeSH
700 1 _ |a Albers, Gregory W
|b 1
700 1 _ |a Dichgans, Martin
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700 1 _ |a Donnan, Geoffrey
|b 3
700 1 _ |a Esposito, Elga
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700 1 _ |a Foster, Russell
|b 5
700 1 _ |a Howells, David W
|b 6
700 1 _ |a Huang, Yi-Ge
|b 7
700 1 _ |a Ji, Xunming
|b 8
700 1 _ |a Klerman, Elizabeth B
|b 9
700 1 _ |a Lee, Sarah
|b 10
700 1 _ |a Li, Wenlu
|b 11
700 1 _ |a Liebeskind, David S
|b 12
700 1 _ |a Lizasoain, Ignacio
|b 13
700 1 _ |a Mandeville, Emiri T
|b 14
700 1 _ |a Moro, Maria A
|b 15
700 1 _ |a Ning, MingMing
|b 16
700 1 _ |a Ray, David
|b 17
700 1 _ |a Sakadžić, Sava
|b 18
700 1 _ |a Saver, Jeffrey L
|b 19
700 1 _ |a Scheer, Frank A J L
|b 20
700 1 _ |a Selim, Magdy
|b 21
700 1 _ |a Tiedt, Steffen
|b 22
700 1 _ |a Zhang, Fang
|b 23
700 1 _ |a Buchan, Alastair M
|b 24
773 _ _ |a 10.1161/STROKEAHA.120.031742
|g Vol. 52, no. 6, p. 2180 - 2190
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|t Stroke
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