000155570 001__ 155570 000155570 005__ 20250414153737.0 000155570 0247_ $$2pmc$$apmc:PMC8803276 000155570 0247_ $$2doi$$a10.1111/jsr.13347 000155570 0247_ $$2pmid$$apmid:33913199 000155570 0247_ $$2ISSN$$a0962-1105 000155570 0247_ $$2ISSN$$a1365-2869 000155570 0247_ $$2altmetric$$aaltmetric:104926420 000155570 037__ $$aDZNE-2021-00748 000155570 041__ $$aEnglish 000155570 082__ $$a610 000155570 1001_ $$00000-0003-3999-3807$$aTahmasian, Masoud$$b0$$eCorresponding author 000155570 245__ $$aENIGMA-Sleep: Challenges, opportunities, and the road map. 000155570 260__ $$aOxford [u.a.]$$bWiley-Blackwell$$c2021 000155570 3367_ $$2DRIVER$$aarticle 000155570 3367_ $$2DataCite$$aOutput Types/Journal article 000155570 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1744637812_21649 000155570 3367_ $$2BibTeX$$aARTICLE 000155570 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000155570 3367_ $$00$$2EndNote$$aJournal Article 000155570 520__ $$aNeuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics and varied methodologies. These issues call for a large-scale multi-centre effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine. 000155570 536__ $$0G:(DE-HGF)POF4-353$$a353 - Clinical and Health Care Research (POF4-353)$$cPOF4-353$$fPOF IV$$x0 000155570 588__ $$aDataset connected to CrossRef, PubMed, , Journals: pub.dzne.de 000155570 650_7 $$2Other$$aENIGMA consortium 000155570 650_7 $$2Other$$alarge-scale collaboration 000155570 650_7 $$2Other$$aneurogenetics 000155570 650_7 $$2Other$$aneuroimaging 000155570 650_7 $$2Other$$asleep 000155570 650_2 $$2MeSH$$aBrain: diagnostic imaging 000155570 650_2 $$2MeSH$$aHumans 000155570 650_2 $$2MeSH$$aNeuroimaging 000155570 650_2 $$2MeSH$$aSample Size 000155570 650_2 $$2MeSH$$aSleep Deprivation 000155570 7001_ $$aAleman, André$$b1 000155570 7001_ $$0P:(DE-2719)9001146$$aAndreassen, Ole A$$b2$$udzne 000155570 7001_ $$00000-0001-6210-4532$$aArab, Zahra$$b3 000155570 7001_ $$aBaillet, Marion$$b4 000155570 7001_ $$aBenedetti, Francesco$$b5 000155570 7001_ $$aBresser, Tom$$b6 000155570 7001_ $$00000-0002-0695-0491$$aBright, Joanna$$b7 000155570 7001_ $$aChee, Michael W L$$b8 000155570 7001_ $$aChylinski, Daphne$$b9 000155570 7001_ $$aCheng, Wei$$b10 000155570 7001_ $$aDeantoni, Michele$$b11 000155570 7001_ $$aDresler, Martin$$b12 000155570 7001_ $$aEickhoff, Simon B$$b13 000155570 7001_ $$aEickhoff, Claudia R$$b14 000155570 7001_ $$aElvsåshagen, Torbjørn$$b15 000155570 7001_ $$aFeng, Jianfeng$$b16 000155570 7001_ $$aFoster-Dingley, Jessica C$$b17 000155570 7001_ $$aGanjgahi, Habib$$b18 000155570 7001_ $$0P:(DE-2719)2811781$$aGrabe, Hans J$$b19$$udzne 000155570 7001_ $$aGroenewold, Nynke A$$b20 000155570 7001_ $$aHo, Tiffany C$$b21 000155570 7001_ $$aBong Hong, Seung$$b22 000155570 7001_ $$00000-0003-3166-5606$$aHouenou, Josselin$$b23 000155570 7001_ $$aIrungu, Benson$$b24 000155570 7001_ 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