TY  - JOUR
AU  - Tahmasian, Masoud
AU  - Aleman, André
AU  - Andreassen, Ole A
AU  - Arab, Zahra
AU  - Baillet, Marion
AU  - Benedetti, Francesco
AU  - Bresser, Tom
AU  - Bright, Joanna
AU  - Chee, Michael W L
AU  - Chylinski, Daphne
AU  - Cheng, Wei
AU  - Deantoni, Michele
AU  - Dresler, Martin
AU  - Eickhoff, Simon B
AU  - Eickhoff, Claudia R
AU  - Elvsåshagen, Torbjørn
AU  - Feng, Jianfeng
AU  - Foster-Dingley, Jessica C
AU  - Ganjgahi, Habib
AU  - Grabe, Hans J
AU  - Groenewold, Nynke A
AU  - Ho, Tiffany C
AU  - Bong Hong, Seung
AU  - Houenou, Josselin
AU  - Irungu, Benson
AU  - Jahanshad, Neda
AU  - Khazaie, Habibolah
AU  - Kim, Hosung
AU  - Koshmanova, Ekaterina
AU  - Kocevska, Desi
AU  - Kochunov, Peter
AU  - Lakbila-Kamal, Oti
AU  - Leerssen, Jeanne
AU  - Li, Meng
AU  - Luik, Annemarie I
AU  - Muto, Vincenzo
AU  - Narbutas, Justinas
AU  - Nilsonne, Gustav
AU  - O'Callaghan, Victoria S
AU  - Olsen, Alexander
AU  - Osorio, Ricardo S
AU  - Poletti, Sara
AU  - Poudel, Govinda
AU  - Reesen, Joyce E
AU  - Reneman, Liesbeth
AU  - Reyt, Mathilde
AU  - Riemann, Dieter
AU  - Rosenzweig, Ivana
AU  - Rostampour, Masoumeh
AU  - Saberi, Amin
AU  - Schiel, Julian
AU  - Schmidt, Christina
AU  - Schrantee, Anouk
AU  - Sciberras, Emma
AU  - Silk, Tim J
AU  - Sim, Kang
AU  - Smevik, Hanne
AU  - Soares, Jair C
AU  - Spiegelhalder, Kai
AU  - Stein, Dan J
AU  - Talwar, Puneet
AU  - Tamm, Sandra
AU  - Teresi, Giana L
AU  - Valk, Sofie L
AU  - Van Someren, Eus
AU  - Vandewalle, Gilles
AU  - Van Egroo, Maxime
AU  - Völzke, Henry
AU  - Walter, Martin
AU  - Wassing, Rick
AU  - Weber, Frederik D
AU  - Weihs, Antoine
AU  - Westlye, Lars Tjelta
AU  - Wright, Margaret J
AU  - Wu, Mon-Ju
AU  - Zak, Nathalia
AU  - Zarei, Mojtaba
TI  - ENIGMA-Sleep: Challenges, opportunities, and the road map.
JO  - Journal of sleep research
VL  - 30
IS  - 6
SN  - 1365-2869
CY  - Oxford [u.a.]
PB  - Wiley-Blackwell
M1  - DZNE-2021-00748
SP  - e13347
PY  - 2021
AB  - Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics and varied methodologies. These issues call for a large-scale multi-centre effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine.
KW  - Brain: diagnostic imaging
KW  - Humans
KW  - Neuroimaging
KW  - Sample Size
KW  - Sleep Deprivation
KW  - ENIGMA consortium (Other)
KW  - large-scale collaboration (Other)
KW  - neurogenetics (Other)
KW  - neuroimaging (Other)
KW  - sleep (Other)
LB  - PUB:(DE-HGF)16
C2  - pmc:PMC8803276
C6  - pmid:33913199
DO  - DOI:10.1111/jsr.13347
UR  - https://pub.dzne.de/record/155570
ER  -