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@ARTICLE{Fritz:155655,
author = {Fritz, Thomas H and Liebau, Gefion and Löhle, Matthias and
Hartjen, Berit and Czech, Phillip and Schneider, Lydia and
Sehm, Bernhard and Kotz, Sonja A and Ziemssen, Tjalf and
Storch, Alexander and Villringer, Arno},
title = {{D}issonance in {M}usic {I}mpairs {S}patial {G}ait
{P}arameters in {P}atients with {P}arkinson's {D}isease.},
journal = {Journal of Parkinson's Disease},
volume = {11},
number = {1},
issn = {1877-718X},
address = {Amsterdam},
publisher = {IOS Press},
reportid = {DZNE-2021-00823},
pages = {363 - 372},
year = {2021},
abstract = {It is known that music influences gait parameters in
Parkinson's disease (PD). However, it remains unclear
whether this effect is merely due to temporal aspects of
music (rhythm and tempo) or other musical parameters.To
examine the influence of pleasant and unpleasant music on
spatiotemporal gait parameters in PD, while controlling for
rhythmic aspects of the musical signal.We measured
spatiotemporal gait parameters of 18 patients suffering from
mild PD $(50\%men,$ mean±SD age of 64±6 years; mean
disease duration of 6±5 years; mean Unified PD Rating scale
[UPDRS] motor score of 15±7) who listened to eight
different pieces of music. Music pieces varied in harmonic
consonance/dissonance to create the experience of
pleasant/unpleasant feelings. To measure gait parameters, we
used an established analysis of spatiotemporal gait, which
consists of a walkway containing pressure-receptive sensors
(GAITRite®). Repeated measures analyses of variance were
used to evaluate effects of auditory stimuli. In addition,
linear regression was used to evaluate effects of valence on
gait.Sensory dissonance modulated spatiotemporal and spatial
gait parameters, namely velocity and stride length, while
temporal gait parameters (cadence, swing duration) were not
affected. In contrast, valence in music as perceived by
patients was not associated with gait parameters. Motor and
musical abilities did not relevantly influence the
modulation of gait by auditory stimuli.Our observations
suggest that dissonant music negatively affects particularly
spatial gait parameters in PD by yet unknown mechanisms, but
putatively through increased cognitive interference reducing
attention in auditory cueing.},
keywords = {Aged / Animals / Auditory Perception: physiology /
Biomechanical Phenomena / Female / Gait Disorders,
Neurologic: etiology / Gait Disorders, Neurologic:
physiopathology / Humans / Male / Middle Aged / Music /
Parkinson Disease: complications / Parkinson Disease:
physiopathology / Pleasure: physiology / Psychomotor
Performance: physiology / Spatio-Temporal Analysis /
Parkinson’s disease (Other) / dopamine (Other) / gait
(Other) / music (Other) / valence (Other)},
cin = {AG Storch},
ddc = {610},
cid = {I:(DE-2719)5000014},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:33285641},
doi = {10.3233/JPD-202413},
url = {https://pub.dzne.de/record/155655},
}