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@ARTICLE{Becker:155675,
      author       = {Becker, Sara and Boettinger, Olga and Sulzer, Patricia and
                      Hobert, Markus A. and Brockmann, Kathrin and Maetzler,
                      Walter and Berg, Daniela and Liepelt-Scarfone, Inga},
      collaboration = {Initiative, Alzheimer’s Disease Neuroimaging},
      title        = {{E}veryday {F}unction in {A}lzheimer's and {P}arkinson's
                      {P}atients with {M}ild {C}ognitive {I}mpairment.},
      journal      = {Journal of Alzheimer's disease},
      volume       = {79},
      number       = {1},
      issn         = {1875-8908},
      address      = {Amsterdam},
      publisher    = {IOS Press},
      reportid     = {DZNE-2021-00843},
      pages        = {197 - 209},
      year         = {2021},
      abstract     = {Instrumental activities of daily living (IADL) impairment
                      can begin in mild cognitive impairment (MCI), and is the
                      core criteria for diagnosing dementia in both Alzheimer's
                      (AD) and Parkinson's (PD) diseases. The Functional
                      Activities Questionnaire (FAQ) has high discriminative power
                      for dementia and MCI in older age populations, but is
                      influenced by demographic factors. It is currently unclear
                      whether the FAQ is suitable for assessing
                      cognitive-associated IADL in non-demented PD patients, as
                      motor disorders may affect ratings.To compare IADL profiles
                      in MCI patients with PD (PD-MCI) and AD (AD-MCI) and to
                      verify the discriminative ability of the FAQ for MCI in
                      patients with (PD-MCI) and without (AD-MCI) additional motor
                      impairment.Data of 42 patients each of PD-MCI, AD-MCI, PD
                      cognitively normal (PD-CN), and healthy controls (HC),
                      matched according to age, gender, education, and global
                      cognitive impairment were analyzed. ANCOVA and binary
                      regressions were used to examine the relationship between
                      the FAQ scores and groups. FAQ cut-offs for PD-MCI (versus
                      PD-NC) and AD-MCI (versus HC) were separately identified
                      using receiver operating characteristic analyses.FAQ total
                      score did not differentiate between MCI groups. PD-MCI
                      subjects had greater difficulties with tax records and
                      traveling while AD-MCI individuals were more impaired in
                      managing finances and remembering appointments.
                      Classification accuracy of the FAQ was good for diagnosing
                      AD-MCI $(69\%,$ cut-off ≥1) compared to HC, and sufficient
                      for differentiating PD-MCI $(38.1\%,$ cut-off ≥3) from
                      PD-CN.The FAQ task profiles and classification accuracy
                      differed between MCI related to PD and AD.},
      keywords     = {Activities of Daily Living / Aged / Alzheimer Disease:
                      physiopathology / Cognitive Dysfunction: physiopathology /
                      Female / Functional Status / Humans / Male / Mental Status
                      and Dementia Tests / Parkinson Disease: physiopathology /
                      Activities of daily living (Other) / Alzheimer’s disease
                      (Other) / Parkinson’s disease (Other) / cognitive
                      dysfunction (Other) / dementia (Other) / mild cognitive
                      impairment (Other)},
      cin          = {AG Gasser / AG Latz ; AG Latz / Core ICRU},
      ddc          = {610},
      cid          = {I:(DE-2719)1210000 / I:(DE-2719)1013024 /
                      I:(DE-2719)1240005},
      pnm          = {353 - Clinical and Health Care Research (POF4-353) / 351 -
                      Brain Function (POF4-351)},
      pid          = {G:(DE-HGF)POF4-353 / G:(DE-HGF)POF4-351},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33216023},
      doi          = {10.3233/JAD-200256},
      url          = {https://pub.dzne.de/record/155675},
}