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@ARTICLE{Babiloni:155732,
      author       = {Babiloni, Claudio and Arakaki, Xianghong and Bonanni, Laura
                      and Bujan, Ana and Carrillo, Maria C and Del Percio, Claudio
                      and Edelmayer, Rebecca M and Egan, Gary and Elahh, Fanny M
                      and Evans, Alan and Ferri, Raffaele and Frisoni, Giovanni B
                      and Güntekin, Bahar and Hainsworth, Atticus and Hampel,
                      Harald and Jelic, Vesna and Jeong, Jaeseung and Kim, Doh
                      Kwan and Kramberger, Milica and Kumar, Sanjeev and Lizio,
                      Roberta and Nobili, Flavio and Noce, Giuseppe and Puce, Aina
                      and Ritter, Petra and Smit, Dirk J A and Soricelli, Andrea
                      and Teipel, Stefan and Tucci, Federico and Sachdev,
                      Perminder and Valdes-Sosa, Mitchell and Valdes-Sosa, Pedro
                      and Vergallo, Andrea and Yener, Görsev},
      title        = {{EEG} measures for clinical research in major vascular
                      cognitive impairment: recommendations by an expert panel.},
      journal      = {Neurobiology of aging},
      volume       = {103},
      issn         = {0197-4580},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DZNE-2021-00900},
      pages        = {78 - 97},
      year         = {2021},
      abstract     = {Vascular contribution to cognitive impairment (VCI) and
                      dementia is related to etiologies that may affect the
                      neurophysiological mechanisms regulating brain arousal and
                      generating electroencephalographic (EEG) activity. A
                      multidisciplinary expert panel reviewed the clinical
                      literature and reached consensus about the EEG measures
                      consistently found as abnormal in VCI patients with
                      dementia. As compared to cognitively unimpaired individuals,
                      those VCI patients showed (1) smaller amplitude of resting
                      state alpha (8-12 Hz) rhythms dominant in posterior regions;
                      (2) widespread increases in amplitude of delta (< 4 Hz) and
                      theta (4-8 Hz) rhythms; and (3) delayed N200/P300 peak
                      latencies in averaged event-related potentials, especially
                      during the detection of auditory rare target stimuli
                      requiring participants' responses in 'oddball' paradigms.
                      The expert panel formulated the following recommendations:
                      (1) the above EEG measures are not specific for VCI and
                      should not be used for its diagnosis; (2) they may be
                      considered as 'neural synchronization' biomarkers to
                      enlighten the relationships between features of the
                      VCI-related cerebrovascular lesions and abnormalities in
                      neurophysiological brain mechanisms; and (3) they may be
                      tested in future clinical trials as prognostic biomarkers
                      and endpoints of interventions aimed at normalizing
                      background brain excitability and vigilance in wakefulness.},
      subtyp        = {Review Article},
      keywords     = {Brain: physiopathology / Cognitive Dysfunction: diagnosis /
                      Cognitive Dysfunction: etiology / Cognitive Dysfunction:
                      physiopathology / Dementia, Vascular: diagnosis / Dementia,
                      Vascular: etiology / Dementia, Vascular: physiopathology /
                      Electroencephalography: methods / Evoked Potentials:
                      physiology / Humans / Rest: physiology / Cerebrovascular
                      disease (CVD) (Other) / Event-related oscillations (EROs)
                      (Other) / Event-related potentials (ERPs) (Other) / Resting
                      state electroencephalographic (rsEEG) rhythms (Other) /
                      Small vessel disease (Other) / Subcortical ischemic vascular
                      disease (Other) / Vascular cognitive impairment (VCI)
                      (Other) / Vascular contribution to cognitive impairment and
                      dementia (VCID) (Other) / Vascular dementia (VaD) (Other)},
      cin          = {AG Teipel},
      ddc          = {610},
      cid          = {I:(DE-2719)1510100},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33845399},
      doi          = {10.1016/j.neurobiolaging.2021.03.003},
      url          = {https://pub.dzne.de/record/155732},
}