000157732 001__ 157732 000157732 005__ 20240328115556.0 000157732 0247_ $$2doi$$a10.3389/fneur.2021.654850 000157732 0247_ $$2pmid$$apmid:34054698 000157732 0247_ $$2pmc$$apmc:PMC8160300 000157732 0247_ $$2altmetric$$aaltmetric:105841238 000157732 037__ $$aDZNE-2021-01189 000157732 041__ $$aEnglish 000157732 082__ $$a610 000157732 1001_ $$0P:(DE-2719)2812560$$aPietrowski, Marie J$$b0$$eFirst author 000157732 245__ $$aGlial Purinergic Signaling in Neurodegeneration. 000157732 260__ $$aLausanne$$bFrontiers Research Foundation$$c2021 000157732 3367_ $$2DRIVER$$aarticle 000157732 3367_ $$2DataCite$$aOutput Types/Journal article 000157732 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1711546509_24240$$xReview Article 000157732 3367_ $$2BibTeX$$aARTICLE 000157732 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000157732 3367_ $$00$$2EndNote$$aJournal Article 000157732 520__ $$aPurinergic signaling regulates neuronal and glial cell functions in the healthy CNS. In neurodegenerative diseases, purinergic signaling becomes dysregulated and can affect disease-associated phenotypes of glial cells. 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