% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Reusch:157739,
      author       = {Reusch, Nico and De Domenico, Elena and Bonaguro, Lorenzo
                      and Schulte-Schrepping, Jonas and Baßler, Kevin and
                      Schultze, Joachim L and Aschenbrenner, Anna Christin},
      title        = {{N}eutrophils in {COVID}-19.},
      journal      = {Frontiers in immunology},
      volume       = {12},
      issn         = {1664-3224},
      address      = {Lausanne},
      publisher    = {Frontiers Media},
      reportid     = {DZNE-2021-01196},
      pages        = {652470},
      year         = {2021},
      abstract     = {Strong evidence has been accumulated since the beginning of
                      the COVID-19 pandemic that neutrophils play an important
                      role in the pathophysiology, particularly in those with
                      severe disease courses. While originally considered to be a
                      rather homogeneous cell type, recent attention to
                      neutrophils has uncovered their fascinating transcriptional
                      and functional diversity as well as their developmental
                      trajectories. These new findings are important to better
                      understand the many facets of neutrophil involvement not
                      only in COVID-19 but also many other acute or chronic
                      inflammatory diseases, both communicable and
                      non-communicable. Here, we highlight the observed immune
                      deviation of neutrophils in COVID-19 and summarize several
                      promising therapeutic attempts to precisely target
                      neutrophils and their reactivity in patients with COVID-19.},
      subtyp        = {Review Article},
      keywords     = {COVID-19: epidemiology / COVID-19: immunology / Humans /
                      Neutrophils: immunology / Pandemics / SARS-CoV-2: immunology
                      / COVID-19 (Other) / SARS-CoV-2 (Other) / clinical trials
                      (Other) / granulocytes (Other) / neutrophils (Other) /
                      scRNA-seq (Other) / viral infection (Other)},
      cin          = {Schultze - PRECISE},
      ddc          = {610},
      cid          = {I:(DE-2719)1013031},
      pnm          = {354 - Disease Prevention and Healthy Aging (POF4-354)},
      pid          = {G:(DE-HGF)POF4-354},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33841435},
      pmc          = {pmc:PMC8027077},
      doi          = {10.3389/fimmu.2021.652470},
      url          = {https://pub.dzne.de/record/157739},
}