%0 Journal Article
%A Rotta, Johanna
%A Perosa, Valentina
%A Yakupov, Renat
%A Kuijf, Hugo J
%A Schreiber, Frank
%A Dobisch, Laura
%A Oltmer, Jan
%A Assmann, Anne
%A Speck, Oliver
%A Heinze, Hans-Jochen
%A Acosta-Cabronero, Julio
%A Düzel, Emrah
%A Schreiber, Stefanie
%T Detection of Cerebral Microbleeds With Venous Connection at 7-Tesla MRI.
%J Neurology
%V 96
%N 16
%@ 1526-632X
%C [S.l.]
%I Ovid
%M DZNE-2021-01271
%P e2048 - e2057
%D 2021
%X Cerebral microbleeds (MBs) are a common finding in patients with cerebral small vessel disease (CSVD) and Alzheimer disease as well as in healthy elderly people, but their pathophysiology remains unclear. To investigate a possible role of veins in the development of MBs, we performed an exploratory study, assessing in vivo presence of MBs with a direct connection to a vein.7-Tesla (7T) MRI was conducted and MBs were counted on quantitative susceptibility mapping (QSM). A submillimeter resolution QSM-based venogram allowed identification of MBs with a direct spatial connection to a vein.A total of 51 people (mean age [SD] 70.5 [8.6] years, 37
%K Aged
%K Cerebral Hemorrhage: diagnostic imaging
%K Cerebral Hemorrhage: etiology
%K Cerebral Hemorrhage: pathology
%K Cerebral Small Vessel Diseases: complications
%K Cerebral Small Vessel Diseases: pathology
%K Female
%K Humans
%K Image Interpretation, Computer-Assisted
%K Magnetic Resonance Imaging
%K Male
%K Middle Aged
%K Neuroimaging: methods
%K Veins: diagnostic imaging
%K Veins: pathology
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:33653897
%R 10.1212/WNL.0000000000011790
%U https://pub.dzne.de/record/157814