%0 Journal Article
%A Vöglein, Jonathan
%A Kostova, Irena
%A Arzberger, Thomas
%A Noachtar, Soheyl
%A Dieterich, Marianne
%A Herms, Jochen
%A Schmitz, Peer
%A Ruf, Viktoria
%A Windl, Otto
%A Roeber, Sigrun
%A Simons, Mikael
%A Höglinger, Günter
%A Danek, Adrian
%A Giese, Armin
%A Levin, Johannes
%T Seizure prevalence in neurodegenerative diseases-a study of autopsy proven cases.
%J European journal of neurology
%V 29
%N 1
%@ 1351-5101
%C Oxford
%I Blackwell Science
%M DZNE-2021-01416
%P 12-18
%D 2022
%Z ISSN 1468-1331 not unique: **2 hits**. (CC BY-NC)
%X Knowledge about the seizure prevalence in the whole symptomatic course, from disease onset to death, in neurodegenerative diseases (ND) is lacking. Therefore, the aim was to investigate seizure prevalence and associated clinical implications in neuropathologically diagnosed ND.Clinical records of cases from the Neurobiobank Munich, Germany, were analyzed. Neuropathological diagnoses of the assessed cases included Alzheimer disease (AD), corticobasal degeneration (CBD), frontotemporal lobar degeneration (FTLD), Lewy body disease (LBD), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Seizure prevalence during the whole symptomatic disease phase was assessed and compared amongst ND. Associations between first clinical symptom and seizure prevalence and between seizures and disease duration were examined.In all, 454 patients with neuropathologically diagnosed ND and with available and meaningful clinical records were investigated (AD, n = 144; LBD, n = 103; PSP, n = 93; FTLD, n = 53; MSA, n = 36; CBD, n = 25). Seizure prevalence was 31.3
%K Autopsy
%K Humans
%K Multiple System Atrophy: epidemiology
%K Multiple System Atrophy: pathology
%K Prevalence
%K Seizures: epidemiology
%K Supranuclear Palsy, Progressive: diagnosis
%K Supranuclear Palsy, Progressive: epidemiology
%K Alzheimer disease (Other)
%K epilepsy (Other)
%K neurodegenerative diseases (Other)
%K seizure prevalence (Other)
%K seizures (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34472165
%R 10.1111/ene.15089
%U https://pub.dzne.de/record/162760