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@ARTICLE{Cardona:163367,
      author       = {Cardona, Maria Isabel and Afi, Adel and Lakicevic, Nemanja
                      and Thyrian, Jochen Rene},
      title        = {{P}hysical {A}ctivity {I}nterventions and {T}heir {E}ffects
                      on {C}ognitive {F}unction in {P}eople with {D}ementia: {A}
                      {S}ystematic {R}eview and {M}eta-{A}nalysis.},
      journal      = {International journal of environmental research and public
                      health},
      volume       = {18},
      number       = {16},
      issn         = {1660-4601},
      address      = {Basel},
      publisher    = {MDPI AG},
      reportid     = {DZNE-2022-00130},
      pages        = {8753},
      year         = {2021},
      note         = {(CC BY)},
      abstract     = {Physical activity (PA) has emerged as an alternative
                      nonpharmacological approach to effectively address the
                      effects of dementia. The primary aim was to identify and
                      summarize PA interventions and their effects on cognitive
                      function among persons with dementia (PwD).A systematic
                      review was conducted with a meta-analysis using different
                      electronic databases, such as PubMed, Embase, APA PsycNET,
                      and the Web of Science. The identified and selected studies
                      were randomized controlled trials (RCTs) that were written
                      in English, published between 2000 and 2020, and implemented
                      among PwD who received a PA intervention and whose cognitive
                      function was measured at baseline and during a
                      follow-up.Twenty-two PA intervention studies met the
                      eligibility criteria and showed a medium-size effect on the
                      cognitive function of PwD, 0.4803 $(95\%$ CI =
                      0.1901-0.7704), with a high percentage of heterogeneity (I2
                      = $86\%,$ p ≤ 0.0001). Moreover, this review complements
                      other reviews by including eight studies that have not
                      previously been considered. Overall, studies have
                      methodological limitations. However, six studies implemented
                      in the past five years have shown more robust methodological
                      designs, including larger sample sizes and more
                      comprehensive measurement tools.It is not yet possible to
                      draw a conclusion on the ideal PA intervention for this
                      population due to the high proportion of heterogeneity
                      within the included studies. More emphasis is needed on the
                      intensity of PA monitoring and adherence to such programs.},
      subtyp        = {Review Article},
      keywords     = {Cognition / Dementia: therapy / Exercise / Humans /
                      cognitive function (Other) / dementia (Other) / physical
                      activity (Other)},
      cin          = {AG Thyrian / AG Hoffmann},
      ddc          = {610},
      cid          = {I:(DE-2719)1510800 / I:(DE-2719)1510600},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34444501},
      pmc          = {pmc:PMC8394441},
      doi          = {10.3390/ijerph18168753},
      url          = {https://pub.dzne.de/record/163367},
}