TY  - JOUR
AU  - Litmeier, Simon
AU  - Meinel, Thomas R
AU  - von Rennenberg, Regina
AU  - Kniepert, Joachim U
AU  - Audebert, Heinrich J
AU  - Endres, Matthias
AU  - Jung, Simon
AU  - Scheitz, Jan F.
AU  - Nolte, Christian
TI  - Coronary angiography in acute ischemic stroke patients: frequency and determinants of pathological findings in a multicenter cohort study.
JO  - Journal of neurology
VL  - 269
IS  - 7
SN  - 0340-5354
CY  - Berlin
PB  - Springer
M1  - DZNE-2022-00241
SP  - 3745-3751
PY  - 2022
N1  - ISSN 1432-1459 not unique: **2 hits**.(CC BY)
AB  - Myocardial injury as indicated by cardiac troponin elevation is associated with poor prognosis in acute stroke patients. Coronary angiography (CAG) is the diagnostic gold-standard to rule-out underlying obstructive coronary artery disease (CAD) in these patients. However, weighing risks and benefits of coronary angiography (CAG) against each other is particularly challenging, because stroke patients undergoing CAG may have a higher risk for secondary intracranial bleeding. Current guidelines remain vague. Thus, the aim of this study was to analyze frequency of pathological findings of CAG and associated clinical factors.We analyzed indications and frequency of CAG performed in acute ischemic stroke patients in clinical routine in two European tertiary care hospitals from 2011 to 2018. All data were obtained retrospectively. Multiple logistic regression analyses were performed to identify variables associated with absence of obstructive coronary artery disease defined as presence of at least one coronary vessel stenosis ≥ 50
KW  - Acute Coronary Syndrome: complications
KW  - Acute Coronary Syndrome: diagnosis
KW  - Coronary Angiography
KW  - Coronary Artery Disease: complications
KW  - Coronary Artery Disease: diagnosis
KW  - Humans
KW  - Ischemic Stroke
KW  - Retrospective Studies
KW  - Risk Factors
KW  - Stroke: complications
KW  - Stroke: diagnostic imaging
KW  - Stroke: epidemiology
KW  - Acute ischemic stroke (Other)
KW  - Heart and brain axis (Other)
KW  - Myocardial injury (Other)
KW  - Stroke-heart-syndrome (Other)
LB  - PUB:(DE-HGF)16
C2  - pmc:PMC9217821
C6  - pmid:35182178
DO  - DOI:10.1007/s00415-022-11001-5
UR  - https://pub.dzne.de/record/163481
ER  -