TY  - JOUR
AU  - Scuteri, Damiana
AU  - Contrada, Marianna
AU  - Tonin, Paolo
AU  - Corasaniti, Maria Tiziana
AU  - Nicotera, Pierluigi
AU  - Bagetta, Giacinto
TI  - Dementia and COVID-19: A Case Report and Literature Review on Pain Management.
JO  - Pharmaceuticals
VL  - 15
IS  - 2
SN  - 1424-8247
CY  - Basel
PB  - MDPI
M1  - DZNE-2022-00256
SP  - 199
PY  - 2022
AB  - The coronavirus disease 2019 (COVID-19) pandemic imposes an unprecedented lifestyle, dominated by social isolation. In this frame, the population to pay the highest price is represented by demented patients. This group faces the highest risk of mortality, in case of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection, and they experience rapid cognitive deterioration, due to lockdown measures that prevent their disease monitoring. This complex landscape mirrors an enhancement of neuropsychiatric symptoms (NPSs), with agitation, delirium and reduced motor performances, particularly in non-communicative patients. Due to the consistent link between agitation and pain in these patients, the use of antipsychotics, increasing the risk of death during COVID-19, can be avoided or reduced through an adequate pain treatment. The most suitable pain assessment scale, also feasible for e-health implementation, is the Mobilization-Observation-Behaviour-Intensity-Dementia (MOBID-2) pain scale, currently under validation in the Italian real-world context. Here, we report the case of an 85-year-old woman suffering from mild cognitive impairment, subjected to off-label treatment with atypical antipsychotics, in the context of undertreated pain, who died during the pandemic from an extensive brain hemorrhage. This underscores the need for appropriate assessment and treatment of pain in demented patients.
KW  - COVID-19 (Other)
KW  - MOBID-2 (Other)
KW  - NPSs (Other)
KW  - dementia (Other)
KW  - pain assessment (Other)
KW  - tele-neurorehabilitation (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:35215311
C2  - pmc:PMC8879883
DO  - DOI:10.3390/ph15020199
UR  - https://pub.dzne.de/record/163496
ER  -