TY  - JOUR
AU  - Heumueller, Stefanie-Elisabeth
AU  - Vorberg, Ina Maja
TI  - Möglicher Einfluss von Viren auf die Ausbreitung von Proteinaggregaten
JO  - Biospektrum
VL  - 28
IS  - 2
SN  - 0947-0867
CY  - Heidelberg
PB  - Spektrum
M1  - DZNE-2022-00509
SP  - 162 - 164
PY  - 2022
N1  - (CC BY)
AB  - Neurodegenerative diseases are associated with misfolding of proteins into highly-ordered amyloid fibrils. These protein aggregates can be transmitted to other cells in which they induce aggregation of proteins of the same kind. Mechanisms of intercellular transfer include direct cell contact or transfer of aggregates within extracellular vesicles. Recent research suggests that viral proteins can increase the intercellular spreading of protein aggregation by promoting the required membrane interactions.
LB  - PUB:(DE-HGF)16
C6  - pmid:35369113
C2  - pmc:PMC8960702
DO  - DOI:10.1007/s12268-022-1730-9
UR  - https://pub.dzne.de/record/163770
ER  -