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@ARTICLE{Wenning:163952,
      author       = {Wenning, Gregor K and Stankovic, Iva and Vignatelli, Luca
                      and Fanciulli, Alessandra and Calandra-Buonaura, Giovanna
                      and Seppi, Klaus and Palma, Jose-Alberto and Meissner,
                      Wassilios G and Krismer, Florian and Berg, Daniela and
                      Cortelli, Pietro and Freeman, Roy and Halliday, Glenda and
                      Höglinger, Günter and Lang, Anthony and Ling, Helen and
                      Litvan, Irene and Low, Phillip and Miki, Yasuo and Panicker,
                      Jalesh and Pellecchia, Maria Teresa and Quinn, Niall and
                      Sakakibara, Ryuji and Stamelou, Maria and Tolosa, Eduardo
                      and Tsuji, Shoji and Warner, Tom and Poewe, Werner and
                      Kaufmann, Horacio},
      title        = {{T}he {M}ovement {D}isorder {S}ociety {C}riteria for the
                      {D}iagnosis of {M}ultiple {S}ystem {A}trophy.},
      journal      = {Movement disorders},
      volume       = {37},
      number       = {6},
      issn         = {0885-3185},
      address      = {New York, NY},
      publisher    = {Wiley},
      reportid     = {DZNE-2022-00626},
      pages        = {1131-1148},
      year         = {2022},
      note         = {(CC BY)},
      abstract     = {The second consensus criteria for the diagnosis of multiple
                      system atrophy (MSA) are widely recognized as the reference
                      standard for clinical research, but lack sensitivity to
                      diagnose the disease at early stages.To develop novel
                      Movement Disorder Society (MDS) criteria for MSA diagnosis
                      using an evidence-based and consensus-based methodology.We
                      identified shortcomings of the second consensus criteria for
                      MSA diagnosis and conducted a systematic literature review
                      to answer predefined questions on clinical presentation and
                      diagnostic tools relevant for MSA diagnosis. The criteria
                      were developed and later optimized using two Delphi rounds
                      within the MSA Criteria Revision Task Force, a survey for
                      MDS membership, and a virtual Consensus Conference.The
                      criteria for neuropathologically established MSA remain
                      unchanged. For a clinical MSA diagnosis a new category of
                      clinically established MSA is introduced, aiming for maximum
                      specificity with acceptable sensitivity. A category of
                      clinically probable MSA is defined to enhance sensitivity
                      while maintaining specificity. A research category of
                      possible prodromal MSA is designed to capture patients in
                      the earliest stages when symptoms and signs are present, but
                      do not meet the threshold for clinically established or
                      clinically probable MSA. Brain magnetic resonance imaging
                      markers suggestive of MSA are required for the diagnosis of
                      clinically established MSA. The number of research
                      biomarkers that support all clinical diagnostic categories
                      will likely grow.This set of MDS MSA diagnostic criteria
                      aims at improving the diagnostic accuracy, particularly in
                      early disease stages. It requires validation in a
                      prospective clinical and a clinicopathological study. ©
                      2022 The Authors. Movement Disorders published by Wiley
                      Periodicals LLC on behalf of International Parkinson and
                      Movement Disorder Society.},
      subtyp        = {Review Article},
      keywords     = {Brain: pathology / Consensus / Humans / Magnetic Resonance
                      Imaging / Multiple System Atrophy: diagnosis / Multiple
                      System Atrophy: pathology / Prospective Studies / diagnosis
                      (Other) / diagnostic criteria (Other) / multiple system
                      atrophy (Other)},
      cin          = {AG Höglinger 2},
      ddc          = {610},
      cid          = {I:(DE-2719)1111015},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pmc          = {pmc:PMC9321158},
      pubmed       = {pmid:35445419},
      doi          = {10.1002/mds.29005},
      url          = {https://pub.dzne.de/record/163952},
}