000164064 001__ 164064 000164064 005__ 20240403103707.0 000164064 0247_ $$2doi$$a10.1080/15622975.2021.2011408 000164064 0247_ $$2pmid$$apmid:35175181 000164064 0247_ $$2ISSN$$a1562-2975 000164064 0247_ $$2ISSN$$a1814-1412 000164064 037__ $$aDZNE-2022-00727 000164064 041__ $$aEnglish 000164064 082__ $$a610 000164064 1001_ $$0P:(DE-2719)2812139$$aKleineidam, Luca$$b0$$eFirst author$$udzne 000164064 245__ $$aThe assessment of cognitive function in the German National Cohort (NAKO) - Associations of demographics and psychiatric symptoms with cognitive test performance. 000164064 260__ $$aAbingdon$$bTaylor & Francis Group$$c2023 000164064 3367_ $$2DRIVER$$aarticle 000164064 3367_ $$2DataCite$$aOutput Types/Journal article 000164064 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1701876393_2029 000164064 3367_ $$2BibTeX$$aARTICLE 000164064 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000164064 3367_ $$00$$2EndNote$$aJournal Article 000164064 520__ $$aTo describe the cognitive test battery of the German National Cohort (NAKO), a population-based mega cohort of 205,000 randomly selected participants, and to examine associations with demographic variables and selected psychiatric and neurological conditions.Initial data from 96,401 participants providing data on the cognitive performance measured by a brief cognitive test battery (12-word list recall task, semantic fluency, Stroop test, digit span backwards) was examined. Test results were summarised in cognitive domain scores using exploratory and confirmatory factor analyses. Associations with sociodemographic and psychiatric factors were analysed using linear regression and generalised additive models.Cognitive test results were best represented by two domain scores reflecting memory and executive functions. Lower cognitive functions were associated with increasing age and male sex. Higher education and absence of childhood trauma were associated with better cognitive function. Moderate to severe levels of anxiety and depression, and a history of stroke, were related to lower cognitive function with a stronger effect on executive function as compared to memory. Some associations with cognition differed by German language proficiency.The NAKO cognitive test battery and the derived cognitive domain scores for memory and executive function are sensitive measures of cognition. 000164064 536__ $$0G:(DE-HGF)POF4-353$$a353 - Clinical and Health Care Research (POF4-353)$$cPOF4-353$$fPOF IV$$x0 000164064 588__ $$aDataset connected to CrossRef, PubMed, , Journals: pub.dzne.de 000164064 650_7 $$2Other$$aCognition 000164064 650_7 $$2Other$$aGerman National Cohort 000164064 650_7 $$2Other$$aNAKO 000164064 650_7 $$2Other$$acognitive ageing 000164064 650_7 $$2Other$$aconfirmatory factor analysis 000164064 650_7 $$2Other$$adepression 000164064 650_2 $$2MeSH$$aHumans 000164064 650_2 $$2MeSH$$aMale 000164064 650_2 $$2MeSH$$aCognition 000164064 650_2 $$2MeSH$$aExecutive Function 000164064 650_2 $$2MeSH$$aNeuropsychological Tests 000164064 650_2 $$2MeSH$$aLanguage 000164064 650_2 $$2MeSH$$aDemography 000164064 7001_ $$0P:(DE-2719)9001773$$aStark, Melina$$b1$$udzne 000164064 7001_ $$aRiedel-Heller, Steffi G$$b2 000164064 7001_ $$aPabst, Alexander$$b3 000164064 7001_ $$aSchmiedek, Florian$$b4 000164064 7001_ $$aStreit, Fabian$$b5 000164064 7001_ $$aRietschel, Marcella$$b6 000164064 7001_ $$aKlinger-König, Johanna$$b7 000164064 7001_ $$0P:(DE-2719)2811781$$aGrabe, Hans J$$b8$$udzne 000164064 7001_ $$aErhardt, Angelika$$b9 000164064 7001_ $$aGelbrich, Götz$$b10 000164064 7001_ $$aSchmidt, Börge$$b11 000164064 7001_ $$aInvestigators, NAKO$$b12$$eCollaboration Author 000164064 7001_ $$aBerger, Klaus$$b13 000164064 7001_ $$0P:(DE-2719)2000057$$aWagner, Michael$$b14$$eLast author$$udzne 000164064 7001_ $$aPeters, Annette$$b15 000164064 7001_ $$aFischer, Beate$$b16 000164064 7001_ $$aLeitzmann, Michael$$b17 000164064 7001_ $$aGreiser, Karin Halina$$b18 000164064 7001_ $$aKaaks, Rudolph$$b19 000164064 7001_ $$aMichels, Karin B$$b20 000164064 7001_ $$aFranzke, Claus-Werner$$b21 000164064 7001_ $$aBrenner, Hermann$$b22 000164064 7001_ $$aHolleczek, Bernd$$b23 000164064 7001_ $$aSchramm, Sara$$b24 000164064 7001_ $$aJöckel, Karl-Heinz$$b25 000164064 7001_ $$aMinnerup, Heike$$b26 000164064 7001_ $$0P:(DE-2719)9000854$$aKarch, André$$b27$$udzne 000164064 7001_ $$aFeinkohl, Insa$$b28 000164064 7001_ $$aPischon, Tobias$$b29 000164064 7001_ $$aKrist, Lilian$$b30 000164064 7001_ $$aWillich, Stefan N$$b31 000164064 7001_ $$aSchulze, Matthias B$$b32 000164064 7001_ $$aCastell, Stefanie$$b33 000164064 7001_ $$aHassenstein, Max J$$b34 000164064 7001_ $$aObi, Nadia$$b35 000164064 7001_ $$aBecher, Heiko$$b36 000164064 7001_ $$aGünther, Kathrin$$b37 000164064 7001_ $$aRach, Stefan$$b38 000164064 7001_ $$aLieb, Wolfgang$$b39 000164064 7001_ $$aSchipf, Sabine$$b40 000164064 7001_ $$aMeinke-Franze, Claudia$$b41 000164064 773__ $$0PERI:(DE-600)2170223-8$$a10.1080/15622975.2021.2011408$$gp. 1 - 15$$n10$$p909 - 923$$tThe world journal of biological psychiatry$$v24$$x1562-2975$$y2023 000164064 8564_ $$uhttps://www.tandfonline.com/doi/full/10.1080/15622975.2021.2011408 000164064 8564_ $$uhttps://pub.dzne.de/record/164064/files/DZNE-2022-00727_Restricted.pdf 000164064 8564_ $$uhttps://pub.dzne.de/record/164064/files/DZNE-2022-00727_SUPP_Restricted.pdf 000164064 8564_ $$uhttps://pub.dzne.de/record/164064/files/DZNE-2022-00727_SUPP_Restricted.pdf?subformat=pdfa$$xpdfa 000164064 8564_ $$uhttps://pub.dzne.de/record/164064/files/DZNE-2022-00727_Restricted.pdf?subformat=pdfa$$xpdfa 000164064 909CO $$ooai:pub.dzne.de:164064$$pVDB 000164064 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2812139$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b0$$kDZNE 000164064 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9001773$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE 000164064 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2811781$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b8$$kDZNE 000164064 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2000057$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b14$$kDZNE 000164064 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)9000854$$aExternal Institute$$b27$$kExtern 000164064 9131_ $$0G:(DE-HGF)POF4-353$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vClinical and Health Care Research$$x0 000164064 9141_ $$y2023 000164064 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-02-02 000164064 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-02-02 000164064 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2023-08-26$$wger 000164064 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bWORLD J BIOL PSYCHIA : 2022$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2023-08-26 000164064 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2023-08-26 000164064 9201_ $$0I:(DE-2719)1011201$$kAG Wagner$$lNeuropsychology$$x0 000164064 9201_ $$0I:(DE-2719)5000001$$kAG Grabe$$lBiomarkers of Dementia in the General Population$$x1 000164064 9201_ $$0I:(DE-2719)1510600$$kAG Hoffmann$$lTranslational Health Care Research$$x2 000164064 980__ $$ajournal 000164064 980__ $$aVDB 000164064 980__ $$aI:(DE-2719)1011201 000164064 980__ $$aI:(DE-2719)5000001 000164064 980__ $$aI:(DE-2719)1510600 000164064 980__ $$aUNRESTRICTED