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000164110 037__ $$aDZNE-2022-00773
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000164110 1001_ $$aLuecken, Malte D$$b0
000164110 245__ $$aThe discovAIR project: a roadmap towards the Human Lung Cell Atlas.
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000164110 520__ $$aThe Human Cell Atlas (HCA) consortium aims to establish an atlas of all organs in the healthy human body at single-cell resolution to increase our understanding of basic biological processes that govern development, physiology and anatomy, and to accelerate diagnosis and treatment of disease. The lung biological network of the HCA aims to generate the Human Lung Cell Atlas as a reference for the cellular repertoire, molecular cell states and phenotypes, and the cell-cell interactions that characterise normal lung homeostasis in healthy lung tissue. Such a reference atlas of the healthy human lung will facilitate mapping the changes in the cellular landscape in disease. The discovAIR project is one of six pilot actions for the HCA funded by the European Commission in the context of the H2020 framework program. DiscovAIR aims to establish the first draft of an integrated Human Lung Cell Atlas, combining single-cell transcriptional and epigenetic profiling with spatially resolving techniques on matched tissue samples, as well as including a number of chronic and infectious diseases of the lung. The integrated Lung Cell Atlas will be available as a resource for the wider respiratory community, including basic and translational scientists, clinical medicine, and the private sector, as well as for patients with lung disease and the interested lay public. We anticipate that the Lung Cell Atlas will be the founding stone for a more detailed understanding of the pathogenesis of lung diseases, guiding the design of novel diagnostics and preventive or curative interventions.
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000164110 650_2 $$2MeSH$$aHumans
000164110 650_2 $$2MeSH$$aLung
000164110 650_2 $$2MeSH$$aLung Diseases
000164110 650_2 $$2MeSH$$aProteomics
000164110 650_2 $$2MeSH$$aThorax
000164110 693__ $$0EXP:(DE-2719)PRECISE-20190321$$5EXP:(DE-2719)PRECISE-20190321$$ePlatform for Single Cell Genomics and Epigenomics at DZNE  University of Bonn$$x0
000164110 7001_ $$00000-0001-6747-7928$$aZaragosi, Laure-Emmanuelle$$b1
000164110 7001_ $$aMadissoon, Elo$$b2
000164110 7001_ $$00000-0001-9686-6295$$aSikkema, Lisa$$b3
000164110 7001_ $$aFirsova, Alexandra B$$b4
000164110 7001_ $$0P:(DE-2719)9000846$$aDe Domenico, Elena$$b5$$udzne
000164110 7001_ $$aKümmerle, Louis$$b6
000164110 7001_ $$0P:(DE-2719)2812564$$aSaglam, Adem$$b7$$udzne
000164110 7001_ $$aBerg, Marijn$$b8
000164110 7001_ $$aGay, Aurore C A$$b9
000164110 7001_ $$00000-0001-7869-4936$$aSchniering, Janine$$b10
000164110 7001_ $$aMayr, Christoph H$$b11
000164110 7001_ $$00000-0002-1643-0705$$aAbalo, Xesús M$$b12
000164110 7001_ $$aLarsson, Ludvig$$b13
000164110 7001_ $$aSountoulidis, Alexandros$$b14
000164110 7001_ $$aTeichmann, Sarah$$b15
000164110 7001_ $$avan Eunen, Karen$$b16
000164110 7001_ $$00000-0001-8567-3252$$aKoppelman, Gerard H$$b17
000164110 7001_ $$aSaeb-Parsy, Kourosh$$b18
000164110 7001_ $$aLeroy, Sylvie$$b19
000164110 7001_ $$aPowell, Pippa$$b20
000164110 7001_ $$aSarkans, Ugis$$b21
000164110 7001_ $$00000-0002-4146-6363$$aTimens, Wim$$b22
000164110 7001_ $$aLundeberg, Joakim$$b23
000164110 7001_ $$avan den Berge, Maarten$$b24
000164110 7001_ $$aNilsson, Mats$$b25
000164110 7001_ $$aHorváth, Peter$$b26
000164110 7001_ $$aDenning, Jessica$$b27
000164110 7001_ $$aPapatheodorou, Irene$$b28
000164110 7001_ $$0P:(DE-2719)2811660$$aSchultze, Joachim$$b29$$udzne
000164110 7001_ $$aSchiller, Herbert B$$b30
000164110 7001_ $$00000-0001-9632-6483$$aBarbry, Pascal$$b31
000164110 7001_ $$aPetoukhov, Ilya$$b32
000164110 7001_ $$aMisharin, Alexander V$$b33
000164110 7001_ $$00000-0003-2101-8843$$aAdcock, Ian$$b34
000164110 7001_ $$avon Papen, Michael$$b35
000164110 7001_ $$aTheis, Fabian J$$b36
000164110 7001_ $$aSamakovlis, Christos$$b37
000164110 7001_ $$aMeyer, Kerstin B$$b38
000164110 7001_ $$00000-0003-3372-6521$$aNawijn, Martijn C$$b39
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