%0 Journal Article
%A Wolfsgruber, Steffen
%A Kleineidam, Luca
%A Weyrauch, Anne Sophie
%A Barkhoff, Miriam
%A Röske, Sandra
%A Peters, Oliver
%A Preis, Lukas
%A Gref, Daria
%A Spruth, Eike Jakob
%A Altenstein, Slawek
%A Priller, Josef
%A Fließbach, Klaus
%A Schneider, Anja
%A Wiltfang, Jens
%A Bartels, Claudia
%A Jessen, Frank
%A Maier, Franziska
%A Düzel, Emrah
%A Metzger, Coraline
%A Glanz, Wenzel
%A Bürger, Katharina
%A Janowitz, Daniel
%A Perneczky, Robert
%A Rauchmann, Boris Stephan
%A Kilimann, Ingo
%A Teipel, Stefan
%A Laske, Christoph
%A Munk, Matthias H
%A Roy, Nina
%A Spottke, Annika
%A Ramirez, Alfredo
%A Heneka, Michael T
%A Brosseron, Frederic
%A Wagner, Michael
%T Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease.
%J Journal of Alzheimer's disease
%V 87
%N 2
%@ 1387-2877
%C Amsterdam
%I IOS Press
%M DZNE-2022-00777
%P 545 - 555
%D 2022
%X It is unclear whether subjective cognitive decline (SCD) is a relevant clinical marker of incipient Alzheimer's disease (AD) and future cognitive deterioration in individuals with a family history of AD (FHAD).To investigate the association of SCD with cross-sectional cerebrospinal fluid (CSF) AD biomarker levels and cognitive decline in cognitively normal older adults with or without a first-degree FHAD.We analyzed data from cognitively normal individuals with first-degree FHAD (n = 82 'AD relatives'; mean age: 65.7 years (SD = 4.47); 59
%K Aged
%K Alzheimer Disease: pathology
%K Biomarkers: cerebrospinal fluid
%K Cognitive Dysfunction: psychology
%K Cross-Sectional Studies
%K Female
%K Humans
%K Male
%K Neuropsychological Tests
%K Alzheimer’s disease (Other)
%K cerebrospinal fluid (Other)
%K family history (Other)
%K subjective cognitive decline (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:35275535
%R 10.3233/JAD-215416
%U https://pub.dzne.de/record/164114