001     164429
005     20240617134721.0
024 7 _ |a 10.1016/S1474-4422(20)30238-6
|2 doi
024 7 _ |a 1474-4422
|2 ISSN
024 7 _ |a 1474-4465
|2 ISSN
024 7 _ |a altmetric:90449688
|2 altmetric
024 7 _ |a pmid:32949547
|2 pmid
037 _ _ |a DZNE-2022-00981
082 _ _ |a 610
100 1 _ |a Lauwers, Elsa
|b 0
245 _ _ |a Potential human transmission of amyloid β pathology: surveillance and risks
260 _ _ |a London
|c 2020
|b Lancet Publ. Group
336 7 _ |a article
|2 DRIVER
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1718624795_25688
|2 PUB:(DE-HGF)
|x Review Article
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a Journal Article
|0 0
|2 EndNote
520 _ _ |a Studies in experimental animals show transmissibility of amyloidogenic proteins associated with prion diseases, Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases. Although these data raise potential concerns for public health, convincing evidence for human iatrogenic transmission only exists for prions and amyloid β after systemic injections of contaminated growth hormone extracts or dura mater grafts derived from cadavers. Even though these procedures are now obsolete, some reports raise the possibility of iatrogenic transmission of amyloid β through putatively contaminated neurosurgical equipment. Iatrogenic transmission of amyloid β might lead to amyloid deposition in the brain parenchyma and blood vessel walls, potentially resulting in cerebral amyloid angiopathy after several decades. Cerebral amyloid angiopathy can cause life-threatening brain haemorrhages; yet, there is no proof that the transmission of amyloid β can also lead to Alzheimer's dementia. Large, long-term epidemiological studies and sensitive, cost-efficient tools to detect amyloid are needed to better understand any potential routes of amyloid β transmission and to clarify whether other similar proteopathic seeds, such as tau or α-synuclein, can also be transferred iatrogenically.
536 _ _ |a 899 - ohne Topic (POF4-899)
|0 G:(DE-HGF)POF4-899
|c POF4-899
|f POF IV
|x 0
588 _ _ |a Dataset connected to CrossRef, Journals: pub.dzne.de
650 _ 2 |a Alzheimer Disease: etiology
|2 MeSH
650 _ 2 |a Alzheimer Disease: metabolism
|2 MeSH
650 _ 2 |a Alzheimer Disease: pathology
|2 MeSH
650 _ 2 |a Amyloid beta-Peptides: metabolism
|2 MeSH
650 _ 2 |a Amyloid beta-Peptides: toxicity
|2 MeSH
650 _ 2 |a Animals
|2 MeSH
650 _ 2 |a Creutzfeldt-Jakob Syndrome: metabolism
|2 MeSH
650 _ 2 |a Creutzfeldt-Jakob Syndrome: pathology
|2 MeSH
650 _ 2 |a Creutzfeldt-Jakob Syndrome: transmission
|2 MeSH
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Neurodegenerative Diseases: etiology
|2 MeSH
650 _ 2 |a Neurodegenerative Diseases: metabolism
|2 MeSH
650 _ 2 |a Neurodegenerative Diseases: pathology
|2 MeSH
650 _ 2 |a Parkinson Disease: etiology
|2 MeSH
650 _ 2 |a Parkinson Disease: metabolism
|2 MeSH
650 _ 2 |a Parkinson Disease: pathology
|2 MeSH
650 _ 2 |a Population Surveillance
|2 MeSH
650 _ 2 |a Risk Factors
|2 MeSH
700 1 _ |a Lalli, Giovanna
|b 1
700 1 _ |a Brandner, Sebastian
|b 2
700 1 _ |a Collinge, John
|b 3
700 1 _ |a Compernolle, Veerle
|b 4
700 1 _ |a Duyckaerts, Charles
|b 5
700 1 _ |a Edgren, Gustaf
|b 6
700 1 _ |a Haïk, Stéphane
|b 7
700 1 _ |a Hardy, John
|b 8
700 1 _ |a Helmy, Adel
|b 9
700 1 _ |a Ivinson, Adrian J
|b 10
700 1 _ |a Jaunmuktane, Zane
|b 11
700 1 _ |a Jucker, Mathias
|0 P:(DE-2719)2000010
|b 12
|u dzne
700 1 _ |a Knight, Richard
|b 13
700 1 _ |a Lemmens, Robin
|b 14
700 1 _ |a Lin, I-Chun
|0 P:(DE-HGF)0
|b 15
700 1 _ |a Love, Seth
|b 16
700 1 _ |a Mead, Simon
|b 17
700 1 _ |a Perry, V Hugh
|b 18
700 1 _ |a Pickett, James
|b 19
700 1 _ |a Poppy, Guy
|b 20
700 1 _ |a Radford, Sheena E
|b 21
700 1 _ |a Rousseau, Frederic
|b 22
700 1 _ |a Routledge, Carol
|b 23
700 1 _ |a Schiavo, Giampietro
|b 24
700 1 _ |a Schymkowitz, Joost
|b 25
700 1 _ |a Selkoe, Dennis J
|b 26
700 1 _ |a Smith, Colin
|b 27
700 1 _ |a Thal, Dietmar R
|b 28
700 1 _ |a Theys, Tom
|b 29
700 1 _ |a Tiberghien, Pierre
|b 30
700 1 _ |a van den Burg, Peter
|b 31
700 1 _ |a Vandekerckhove, Philippe
|b 32
700 1 _ |a Walton, Clare
|b 33
700 1 _ |a Zaaijer, Hans L
|b 34
700 1 _ |a Zetterberg, Henrik
|b 35
700 1 _ |a De Strooper, Bart
|b 36
773 _ _ |a 10.1016/S1474-4422(20)30238-6
|g Vol. 19, no. 10, p. 872 - 878
|0 PERI:(DE-600)2079704-7
|n 10
|p 872 - 878
|t The lancet / Neurology
|v 19
|y 2020
|x 1474-4422
856 4 _ |u https://pub.dzne.de/record/164429/files/DZNE-2022-00981_Restricted.pdf
856 4 _ |u https://pub.dzne.de/record/164429/files/DZNE-2022-00981_Restricted.pdf?subformat=pdfa
|x pdfa
909 C O |p VDB
|o oai:pub.dzne.de:164429
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 12
|6 P:(DE-2719)2000010
913 1 _ |a DE-HGF
|b Programmungebundene Forschung
|l ohne Programm
|1 G:(DE-HGF)POF4-890
|0 G:(DE-HGF)POF4-899
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-800
|4 G:(DE-HGF)POF
|v ohne Topic
|x 0
914 1 _ |y 2020
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0160
|2 StatID
|b Essential Science Indicators
|d 2021-02-04
915 _ _ |a WoS
|0 StatID:(DE-HGF)0113
|2 StatID
|b Science Citation Index Expanded
|d 2021-02-04
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
|d 2022-11-09
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0199
|2 StatID
|b Clarivate Analytics Master Journal List
|d 2022-11-09
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0150
|2 StatID
|b Web of Science Core Collection
|d 2022-11-09
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1110
|2 StatID
|b Current Contents - Clinical Medicine
|d 2022-11-09
915 _ _ |a JCR
|0 StatID:(DE-HGF)0100
|2 StatID
|b LANCET NEUROL : 2021
|d 2022-11-09
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
|d 2022-11-09
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0600
|2 StatID
|b Ebsco Academic Search
|d 2022-11-09
915 _ _ |a Peer Review
|0 StatID:(DE-HGF)0030
|2 StatID
|b ASC
|d 2022-11-09
915 _ _ |a IF >= 50
|0 StatID:(DE-HGF)9950
|2 StatID
|b LANCET NEUROL : 2021
|d 2022-11-09
920 1 _ |0 I:(DE-2719)1210001
|k AG Jucker
|l Cell Biology of Neurological Diseases
|x 0
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a I:(DE-2719)1210001
980 _ _ |a UNRESTRICTED


LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21