000164544 001__ 164544 000164544 005__ 20240313115346.0 000164544 0247_ $$2doi$$a10.1016/j.biopha.2022.113013 000164544 0247_ $$2ISSN$$a0300-0893 000164544 0247_ $$2ISSN$$a0753-3322 000164544 0247_ $$2ISSN$$a1950-6007 000164544 0247_ $$2altmetric$$aaltmetric:129999536 000164544 0247_ $$2pmid$$apmid:35658247 000164544 037__ $$aDZNE-2022-01093 000164544 082__ $$a610 000164544 1001_ $$aScuteri, D.$$b0 000164544 245__ $$aPain and agitation treatment in severe dementia patients: The need for Italian Mobilization–Observation–Behavior–Intensity–Dementia (I-MOBID2) pain scale translation, adaptation and validation with psychometric testing 000164544 260__ $$aParis [u.a.]$$bElsevier$$c2022 000164544 3367_ $$2DRIVER$$aarticle 000164544 3367_ $$2DataCite$$aOutput Types/Journal article 000164544 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1655112456_6958 000164544 3367_ $$2BibTeX$$aARTICLE 000164544 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000164544 3367_ $$00$$2EndNote$$aJournal Article 000164544 500__ $$aISSN 0753-3322 not unique: **2 hits**.(CC BY-NC-ND 4.0) 000164544 520__ $$aThe 97% of dementia patients develops fluctuant neuropsychiatric symptoms often related to under-diagnosed and unrelieved pain. Up to 80% severe demented nursing home residents experiences chronic pain due to age-related comorbidities. Patients lacking self-report skills risk not to be appropriately treated for pain. Mobilization–Observation–Behavior–Intensity–Dementia (MOBID2) is the sole pain scale to consider the frequent co-occurrence of musculoskeletal and visceral pain and to unravel concealed pain through active guided movements. Accordingly, the Italian real-world setting can benefit from its translation and validation. This clinical study provides a translated, adapted and validated version of the MOBID2, the Italian I-MOBID2. The translation, adaptation and validation of the scale for non-verbal, severe demented patients was conducted according to current guidelines in a cohort of 11 patients over 65 with mini-mental state examination ≤ 12. The I-MOBID2 proves: good face and scale content validity index (0.89); reliable internal consistency (Cronbach’s α = 0.751); good to excellent inter-rater (Intraclass correlation coefficient, and test-retest (ICC = 0.902) reliability. The construct validity is high (Rho = 0.748 p < 0.05 for 11 patients, Spearman rank order correlation of the overall pain intensity score with the maximum item score of I-MOBID2 Part 1; rho=0.895 p < 0.01 for 11 patients, for the overall pain intensity score with the maximum item score of I-MOBID2 Part 2) and a good rate of inter-rater and test-retest agreement was demonstrated by Cohen’s K = 0.744. The average execution time is of 5.8 min, thus making I-MOBID2 a useful tool suitable also for future development in community setting with administration by caregivers. 000164544 536__ $$0G:(DE-HGF)POF4-351$$a351 - Brain Function (POF4-351)$$cPOF4-351$$fPOF IV$$x0 000164544 588__ $$aDataset connected to CrossRef, Journals: pub.dzne.de 000164544 650_2 $$2MeSH$$aChronic Pain: psychology 000164544 650_2 $$2MeSH$$aDementia: therapy 000164544 650_2 $$2MeSH$$aHumans 000164544 650_2 $$2MeSH$$aPain Measurement 000164544 650_2 $$2MeSH$$aPsychometrics 000164544 650_2 $$2MeSH$$aReproducibility of Results 000164544 650_2 $$2MeSH$$aSurveys and Questionnaires 000164544 7001_ $$aContrada, M.$$b1 000164544 7001_ $$aLoria, T.$$b2 000164544 7001_ $$aSturino, D.$$b3 000164544 7001_ $$aCerasa, A.$$b4 000164544 7001_ $$aTonin, P.$$b5 000164544 7001_ $$aSandrini, G.$$b6 000164544 7001_ $$aTamburin, S.$$b7 000164544 7001_ $$aBruni, A. C.$$b8 000164544 7001_ $$0P:(DE-2719)2010732$$aNicotera, P.$$b9$$udzne 000164544 7001_ $$aCorasaniti, M. T.$$b10 000164544 7001_ $$aBagetta, G.$$b11 000164544 773__ $$0PERI:(DE-600)392415-4$$a10.1016/j.biopha.2022.113013$$gVol. 150, p. 113013 -$$p113013$$tBiomedicine & pharmacotherapy$$v150$$x0300-0893$$y2022 000164544 8564_ $$uhttps://pub.dzne.de/record/164544/files/DZNE-2022-01093.pdf$$yOpenAccess 000164544 8564_ $$uhttps://pub.dzne.de/record/164544/files/DZNE-2022-01093.pdf?subformat=pdfa$$xpdfa$$yOpenAccess 000164544 909CO $$ooai:pub.dzne.de:164544$$popenaire$$popen_access$$pVDB$$pdriver$$pdnbdelivery 000164544 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2010732$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b9$$kDZNE 000164544 9131_ $$0G:(DE-HGF)POF4-351$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vBrain Function$$x0 000164544 9141_ $$y2022 000164544 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS 000164544 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences 000164544 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search 000164544 915__ $$0LIC:(DE-HGF)CCBYNCND4$$2HGFVOC$$aCreative Commons Attribution-NonCommercial-NoDerivs CC BY-NC-ND 4.0 000164544 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bBIOMED PHARMACOTHER : 2015 000164544 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection 000164544 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index 000164544 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded 000164544 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5 000164544 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess 000164544 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC 000164544 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database 000164544 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews 000164544 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline 000164544 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List 000164544 9201_ $$0I:(DE-2719)1030000$$kScientific board$$lScientific board$$x0 000164544 9201_ $$0I:(DE-2719)1013003$$kAG Bano$$lAging and neurodegeneration$$x1 000164544 980__ $$ajournal 000164544 980__ $$aVDB 000164544 980__ $$aUNRESTRICTED 000164544 980__ $$aI:(DE-2719)1030000 000164544 980__ $$aI:(DE-2719)1013003 000164544 9801_ $$aFullTexts