000164942 001__ 164942
000164942 005__ 20240311115322.0
000164942 0247_ $$2doi$$a10.1016/j.semcdb.2022.07.001
000164942 0247_ $$2pmid$$apmid:35817655
000164942 0247_ $$2ISSN$$a1084-9521
000164942 0247_ $$2ISSN$$a1096-3634
000164942 0247_ $$2altmetric$$aaltmetric:131471989
000164942 037__ $$aDZNE-2022-01346
000164942 041__ $$aEnglish
000164942 082__ $$a570
000164942 1001_ $$0P:(DE-2719)9000994$$aAlfadil, Eissa$$b0$$eFirst author$$udzne
000164942 245__ $$aMoving through the crowd. Where are we at understanding physiological axon growth?
000164942 260__ $$aLondon$$bAcademic Press$$c2023
000164942 3367_ $$2DRIVER$$aarticle
000164942 3367_ $$2DataCite$$aOutput Types/Journal article
000164942 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1674833043_30746$$xReview Article
000164942 3367_ $$2BibTeX$$aARTICLE
000164942 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000164942 3367_ $$00$$2EndNote$$aJournal Article
000164942 500__ $$aCC BY
000164942 520__ $$aAxon growth enables the rapid wiring of the central nervous system. Understanding this process is a prerequisite to retriggering it under pathological conditions, such as a spinal cord injury, to elicit axon regeneration. The last decades saw progress in understanding the mechanisms underlying axon growth. Most of these studies employed cultured neurons grown on flat surfaces. Only recently studies on axon growth were performed in 3D. In these studies, physiological environments exposed more complex and dynamic aspects of axon development. Here, we describe current views on axon growth and highlight gaps in our knowledge. We discuss how axons interact with the extracellular matrix during development and the role of the growth cone and its cytoskeleton within. Finally, we propose that the time is ripe to study axon growth in a more physiological setting. This will help us uncover the physiologically relevant mechanisms underlying axon growth, and how they can be reactivated to induce axon regeneration.
000164942 536__ $$0G:(DE-HGF)POF4-351$$a351 - Brain Function (POF4-351)$$cPOF4-351$$fPOF IV$$x0
000164942 588__ $$aDataset connected to CrossRef, PubMed, , Journals: pub.dzne.de
000164942 650_7 $$2Other$$aAxon growth
000164942 650_7 $$2Other$$aCytoskeleton
000164942 650_7 $$2Other$$aGrowth cone
000164942 650_7 $$2Other$$aNeuronal polarisation
000164942 650_2 $$2MeSH$$aAxons: physiology
000164942 650_2 $$2MeSH$$aNerve Regeneration
000164942 650_2 $$2MeSH$$aNeurons
000164942 650_2 $$2MeSH$$aCentral Nervous System
000164942 650_2 $$2MeSH$$aNeurogenesis: physiology
000164942 650_2 $$2MeSH$$aGrowth Cones
000164942 7001_ $$0P:(DE-2719)2810270$$aBradke, Frank$$b1$$eLast author$$udzne
000164942 773__ $$0PERI:(DE-600)1471746-3$$a10.1016/j.semcdb.2022.07.001$$gp. S1084952122002300$$p63-71$$tSeminars in cell & developmental biology$$v140$$x1084-9521$$y2023
000164942 8564_ $$uhttps://pub.dzne.de/record/164942/files/DZNE-2022-01346.pdf$$yOpenAccess
000164942 8564_ $$uhttps://pub.dzne.de/record/164942/files/DZNE-2022-01346.pdf?subformat=pdfa$$xpdfa$$yOpenAccess
000164942 909CO $$ooai:pub.dzne.de:164942$$pdnbdelivery$$pdriver$$popenaire$$pVDB$$popen_access
000164942 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9000994$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b0$$kDZNE
000164942 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2810270$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE
000164942 9131_ $$0G:(DE-HGF)POF4-351$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vBrain Function$$x0
000164942 9141_ $$y2023
000164942 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-08-22
000164942 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000164942 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)1040$$2StatID$$aDBCoverage$$bZoological Record$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bSEMIN CELL DEV BIOL : 2022$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2021-02-04
000164942 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000164942 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)9905$$2StatID$$aIF >= 5$$bSEMIN CELL DEV BIOL : 2022$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)1120$$2StatID$$aDBCoverage$$bBIOSIS Reviews Reports And Meetings$$d2023-08-22
000164942 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2021-02-04
000164942 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2023-08-22$$wger
000164942 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-08-22
000164942 9201_ $$0I:(DE-2719)1013002$$kAG Bradke$$lAxon Growth and Regeneration$$x0
000164942 980__ $$ajournal
000164942 980__ $$aVDB
000164942 980__ $$aUNRESTRICTED
000164942 980__ $$aI:(DE-2719)1013002
000164942 9801_ $$aFullTexts