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@ARTICLE{Lahti:165114,
      author       = {Lahti, Jari and Tuominen, Samuli and Yang, Qiong and
                      Pergola, Giulio and Ahmad, Shahzad and Amin, Najaf and
                      Armstrong, Nicola J and Beiser, Alexa and Bey, Katharina and
                      Bis, Joshua C and Boerwinkle, Eric and Bressler, Jan and
                      Campbell, Archie and Campbell, Harry and Chen, Qiang and
                      Corley, Janie and Cox, Simon R and Davies, Gail and De
                      Jager, Philip L and Derks, Eske M and Faul, Jessica D and
                      Fitzpatrick, Annette L and Fohner, Alison E and Ford, Ian
                      and Fornage, Myriam and Gerring, Zachary and Grabe, Hans and
                      Grodstein, Francine and Gudnason, Vilmundur and Simonsick,
                      Eleanor and Holliday, Elizabeth G and Joshi, Peter K and
                      Kajantie, Eero and Kaprio, Jaakko and Karell, Pauliina and
                      Kleineidam, Luca and Knol, Maria J and Kochan, Nicole A and
                      Kwok, John B and Leber, Markus and Lam, Max and Lee, Teresa
                      and Li, Shuo and Loukola, Anu and Luck, Tobias and Marioni,
                      Riccardo E and Mather, Karen A and Medland, Sarah and Mirza,
                      Saira S and Nalls, Mike A and Nho, Kwangsik and O'Donnell,
                      Adrienne and Oldmeadow, Christopher and Painter, Jodie and
                      Pattie, Alison and Reppermund, Simone and Risacher, Shannon
                      L and Rose, Richard J and Sadashivaiah, Vijay and Scholz,
                      Markus and Satizabal, Claudia L and Schofield, Peter W and
                      Schraut, Katharina E and Scott, Rodney J and Simino,
                      Jeannette and Smith, Albert V and Smith, Jennifer A and
                      Stott, David J and Surakka, Ida and Teumer, Alexander and
                      Thalamuthu, Anbupalam and Trompet, Stella and Turner,
                      Stephen T and van der Lee, Sven J and Villringer, Arno and
                      Völker, Uwe and Wilson, Robert S and Wittfeld, Katharina
                      and Vuoksimaa, Eero and Xia, Rui and Yaffe, Kristine and Yu,
                      Lei and Zare, Habil and Zhao, Wei and Ames, David and Attia,
                      John and Bennett, David A and Brodaty, Henry and Chasman,
                      Daniel I and Goldman, Aaron L and Hayward, Caroline and
                      Ikram, M Arfan and Jukema, J Wouter and Kardia, Sharon L R
                      and Lencz, Todd and Loeffler, Markus and Mattay, Venkata S
                      and Palotie, Aarno and Psaty, Bruce M and Ramirez, Alfredo
                      and Ridker, Paul M and Riedel-Heller, Steffi G and Sachdev,
                      Perminder S and Saykin, Andrew J and Scherer, Martin and
                      Schofield, Peter R and Sidney, Stephen and Starr, John M and
                      Trollor, Julian and Ulrich, William and Wagner, Michael and
                      Weir, David R and Wilson, James F and Wright, Margaret J and
                      Weinberger, Daniel R and Debette, Stephanie and Eriksson,
                      Johan G and Mosley, Thomas H and Launer, Lenore J and van
                      Duijn, Cornelia M and Deary, Ian J and Seshadri, Sudha and
                      Räikkönen, Katri},
      title        = {{G}enome-wide meta-analyses reveal novel loci for verbal
                      short-term memory and learning.},
      journal      = {Molecular psychiatry},
      volume       = {27},
      number       = {11},
      issn         = {1359-4184},
      address      = {London},
      publisher    = {Macmillan},
      reportid     = {DZNE-2022-01421},
      pages        = {4419-4431},
      year         = {2022},
      note         = {CC BY: https://creativecommons.org/licenses/by/4.0/},
      abstract     = {Understanding the genomic basis of memory processes may
                      help in combating neurodegenerative disorders. Hence, we
                      examined the associations of common genetic variants with
                      verbal short-term memory and verbal learning in adults
                      without dementia or stroke (N = 53,637). We identified novel
                      loci in the intronic region of CDH18, and at 13q21 and
                      3p21.1, as well as an expected signal in the
                      APOE/APOC1/TOMM40 region. These results replicated in an
                      independent sample. Functional and bioinformatic analyses
                      supported many of these loci and further implicated POC1. We
                      showed that polygenic score for verbal learning associated
                      with brain activation in right parieto-occipital region
                      during working memory task. Finally, we showed genetic
                      correlations of these memory traits with several
                      neurocognitive and health outcomes. Our findings suggest a
                      role of several genomic loci in verbal memory processes.},
      keywords     = {Memory, Short-Term: physiology / Learning / Verbal Learning
                      / Multifactorial Inheritance / Brain},
      cin          = {AG Wagner / AG Grabe / AG Hoffmann},
      ddc          = {610},
      cid          = {I:(DE-2719)1011201 / I:(DE-2719)5000001 /
                      I:(DE-2719)1510600},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pmc          = {pmc:PMC9734053},
      pubmed       = {pmid:35974141},
      doi          = {10.1038/s41380-022-01710-8},
      url          = {https://pub.dzne.de/record/165114},
}